Arizona Cardinals vs Los Angeles Rams Prediction: Arizona has nothing to lose and the Rams are under pressure to bounce back

Arizona Cardinals vs Los Angeles Rams: Prediction for the match on December 07, 2025

The Arizona Cardinals will play the Los Angeles Rams at State Farm Stadium in Week 14. The Rams want to get back on track after losing to the Carolina Panthers 31-28. Even so, they've been doing well lately, winning four of their last five games, including big ones against Tampa Bay, Seattle, and New Orleans. But Arizona is having a hard time. They lost to Tampa Bay 20-17 in their last game, making it four losses in a row. Three of those losses were by a wide margin, and their season is quickly coming to an end. Here at Telecom Asia, we break down the matchup and share the top betting picks for this exciting clash.

Arizona Cardinals Form and Statistics

Jacoby Brissett has thrown for 2,188 yards this year, with 13 touchdowns and 4 interceptions. He completes 67.5% of his passes, averaging 243.1 yards per game and 7.2 yards per attempt. On the ground, he has 116 rushing yards and one rushing touchdown. Trey McBride leads the team with 879 receiving yards (sixth in the NFL) and eight touchdowns (third in the NFL) on 88 receptions (first in the NFL). He’s been targeted 118 times. Marvin Harrison Jr. has 594 receiving yards and 4 touchdowns on 40 receptions, with 69 targets this season. Bam Knight averages 25.5 rushing yards per game, totaling 255 yards with 4 rushing touchdowns. He has also caught 19 passes for 142 yards (eighth on the Cardinals) and one touchdown, averaging 14.2 yards per game. On defense, Josh Sweat has 25 tackles, 12.0 TFL, and 11 sacks through 12 games. Akeem Davis-Gaither has one interception, 68 tackles, 2.0 TFL, and 4 passes defended. Budda Baker leads the Cardinals in tackles with 87, adding 2.0 TFL, 0.5 sacks, and one interception. Jalen Thompson has 74 tackles, 2.0 TFL, one sack, and 6 passes defended in 12 games.

Arizona Cardinals Team News

Jacoby Brissett has thrown for 2,188 yards and only four interceptions, keeping Arizona in the game. However, the offense struggles to make big plays. Bam Knight leads the run game with 255 yards and four touchdowns. Trey McBride has 879 yards and eight touchdowns, standing out as a key player. The main issue is consistency throughout all four quarters.

Cardinals Injury Report: Dadrion Taylor-Demerson, S - Questionable , Walter Nolen III, DT - Questionable , Max Melton, CB - Questionable , Emari Demarcado, RB - Questionable , Hayden Conner, G - Questionable.

Los Angeles Rams: Form and Statistics

Matthew Stafford ranks fifth in the NFL with 3,073 passing yards over 12 games. He averages 256.1 yards per game and has a 66.3% completion rate. He’s thrown 32 touchdowns (most in the NFL) and four interceptions. Kyren Williams has 868 rushing yards, ranking ninth in the league. He averages 72.3 yards per game and has scored seven touchdowns. His 4.7 yards per carry rank 13th in the NFL. Williams also has 24 catches for 184 yards and three receiving touchdowns. Davante Adams has 689 receiving yards and 52 catches through 12 games. He averages 57.4 yards and 4.3 receptions per game. He’s been targeted 99 times and leads the NFL with 14 receiving touchdowns. Puka Nacua has 86 receptions, ranking second in the league, for 1,019 yards, third in the NFL. He averages 92.6 yards and 7.8 catches per game in 11 games. He’s scored four touchdowns and been targeted 107 times.

Los Angeles Rams: Team News

On Wednesday, Kyren Williams, Kamren Kinchens, Omar Speights, and Byron Young were limited in practice. McVay expects all of them to be ready to play. Davante Adams, Darious Williams, and Poona Ford did not practice, but this was part of a maintenance plan.

Rams Injury Report: Quentin Lake, S - IR, Tutu Atwell, WR - IR-R, Roger McCreary, CB - IR, Rob Havenstein, OT - IR, Tyler Higbee, TE - IR.

Arizona Cardinals vs Los Angeles Rams Betting Tips & Odds

• In the last five meetings, Los Angeles has won three times against Arizona. Arizona has been outscored by an average of 3 points in those games.
• The Rams have played 12 games this season, winning 8 against the spread. They’ve covered once this year (1-1 ATS) when favored by 9.5 points or more.
• Los Angeles has gone over the point total in 41.7% of their games (five times in 12). As moneyline favorites, they’ve won 9 of 11 games, or 81.8%. The Rams have an 83.9% chance to win based on the moneyline.
• Arizona is 6-6 ATS this season. They’ve been underdogs by 9.5 points or more once and covered the spread. Seven of their games have gone over the point total. The Cardinals have won one of their nine games as underdogs. Sportsbooks give Arizona a 20.4% chance to win based on the moneyline.

Arizona Cardinals vs Los Angeles Rams Match Prediction 7th December 2025

The Rams have strong talent at almost every position. However, their recent struggles on the road and Arizona’s improved play under Brissett make this game closer than expected. Los Angeles should win, but the 8.5-point spread is too high. The Rams have covered only once in their last three road games. Arizona’s nothing-to-lose mindset in this divisional matchup, along with a 4-3 ATS record under Brissett, suggests they’ll keep the game tight.

Our match prediction is -10.0 Spread Los Angeles Rams with odds at 1.90 on the 1Xbet bookmaker.

Our betting tip is Under 47.5 Total with odds at 1.90 on the Bet365 bookmaker.

Our final match prediction is the -3.5 Spread 1st Half Drive line 2-way with odds at 1.90 on the Betway bookmaker.