Buffalo Bills vs Kansas City Chiefs Prediction: Kansas City Chiefs to get a close narrow victory

Buffalo Bills
Buffalo Bills
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02 Nov 2025 21:00
Kansas City Chiefs
Kansas City Chiefs
Muhydeen Murphy
02 Nov 2025
12:42
Statistics of the month:
15
7
0
68.18%
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Odds 1,76
Bet Type Kansas City Chiefs to win
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Buffalo Bills vs Kansas City Chiefs: Prediction for the match on November 02, 2025

The Kansas City Chiefs (5-3) are on a three-game win streak and will face the Buffalo Bills (5-2) on Sunday, Nov. 2, at Highmark Stadium. The Chiefs are slight favorites (-1.5), and the over/under is set at 52.5 points. This matchup feels more like a battle for AFC dominance than just another game. Both teams are above .500 and eyeing playoff spots. But, the Bills have had a rough week, with injuries making their camp look more like a healing tent. Here at Telecom Asia, we break down the matchup and share the top betting picks for this exciting clash.

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Josh Allen has thrown for 1,560 yards this season, with 12 touchdowns and four interceptions. He completes 68% of his passes. Allen has also rushed for 261 yards and five touchdowns, ranking second on the Bills. James Cook has rushed for 753 yards, averaging 6 yards per carry and 107.6 yards per game. He has scored seven rushing touchdowns. Cook also has 12 catches for 89 yards, with 14 targets and an average of 12.7 yards per game. Khalil Shakir has 356 receiving yards and three touchdowns on 31 receptions, with 41 targets this season. Dalton Kincaid has 21 catches for 310 yards and three touchdowns. He averages 3.5 yards per game and has been targeted 27 times.

On defense, Joey Bosa leads the Bills with three sacks, three TFL, and 16 tackles over seven games. Cole Bishop leads the team in tackles with 34, adding two TFL, two sacks, and one interception. Terrel Bernard has 30 tackles, three TFL, and one interception this season. Greg Rousseau has 18 tackles, three TFL, and 2.5 sacks.

Patrick Mahomes has 2,099 passing yards this season, ranking second in the NFL. He leads the league with 17 touchdowns and has four interceptions. Mahomes completes 67% of his passes, averaging 262.4 yards per game and 7.4 yards per attempt. He also has 280 rushing yards (35 per game) and four rushing touchdowns. Travis Kelce has 37 catches for 474 yards and three touchdowns. He averages 4.6 catches and 59.3 yards per game. Kareem Hunt has rushed for 245 yards and four touchdowns, averaging 30.6 yards per game. He also has eight catches for 57 yards and one touchdown. Marquise Brown has 316 receiving yards, with 32 catches and four touchdowns. He averages four receptions and 39.5 yards per game, with 49 total targets.

On defense, Nick Bolton leads with 61 tackles and four TFL. George Karlaftis III has 26 tackles, seven TFL, and 4.5 sacks. Chamarri Conner has 57 tackles, while Drue Tranquill has 37 tackles, four TFL, two sacks, and one pass defended.

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  • Buffalo has won three of the last five matchups against Kansas City. In those games, the Chiefs have been outscored by 10 points.
  • Kansas City is 5-3 against the spread this season. When favored by 1.5 points or more, they are 4-2 ATS. The Chiefs have hit the over three times in eight games this season (37.5%).
  • They have also won four of six games as the moneyline favorite, with a 66.7% win rate. The moneyline gives them a 56.5% chance to win this matchup.
  • Buffalo is 3-4 against the spread this season. They covered the spread in their only game as underdogs by 1.5 points or more.
  • The Bills have hit the over four times this season. They won their only game as underdogs this year. The implied probability for Buffalo to win is 47.6%.

The Chiefs are still the AFC champions, so this game could be a preview of the AFC Championship. Patrick Mahomes and the Kansas City Chiefs are ready to win a thrilling game in Buffalo. The Bills have beaten the Chiefs four times in a row, including three times in Kansas City and last season's classic win in Orchard Park. But things are different now. Kansas City's roster is better, and the Bills are missing important defensive tackles like Ed Oliver, DaQuan Jones, and TJ Sanders, so it's hard to see them having the same success again. Cook can help the Bills a lot, but they will need more help to win this game.

Our match prediction is -2.0 Spread Kansas City Chiefs with odds at 1.90 on the 1Xbet bookmaker.

Our betting tip is Under 52.5 Total with odds at 1.90 on the Bet365 bookmaker.

Our final match prediction is the Kansas City Chiefs to win with odds at 1.76 on the Betway bookmaker.

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Odds 1,76
Bet Type Kansas City Chiefs to win
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Odds 1,90
Bet Type -2.0 Spread Kansas City Chiefs
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Odds 1,90
Bet Type Under 52.5 Totals
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