The thrilling Serie A 2025-26 season will kick off with its entertaining round fixture showdown on the 23rd of August 2025, with reigning champions Napoli heading to the Mapei Stadium to take on Sassuolo in the opening round. Last season delivered an incredible title race, with Antonio Conte's Napoli clinched the Scudetto with a decisive 2-0 victory over Cagliari at the Stadio Diego Armando Maradona on the final matchday. The championship was decided by the slimmest of margins, with Napoli finishing on 82 points, just one ahead of runners-up Inter Milan, who ended their campaign with 81 points. Telecomasia Sport experts have taken a close look at the favorites to win the Premier League in 2025-26, including the betting odds available.
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Serie A Outright and Top Four Odds
| Teams | To Win Outright Odds | To Finish in Top 4 Odds | To be Relegated Odds |
|---|---|---|---|
| Napoli | 2.62 | 1.22 | 501.00 |
| Inter Milan | 3.75 | 1.33 | 251.00 |
| Juventus | 6.00 | 1.57 | 501.00 |
| AC Milan | 6.50 | 1.67 | 351.00 |
| Roma | 11.00 | 2.37 | 251.00 |
| Atalanta | 21.00 | 3.75 | 101.00 |
| Lazio | 34.00 | 5.50 | 26.00 |
| Como | 67.00 | 5.50 | 34.00 |
| Fiorentina | 67.00 | 6.00 | 34.00 |
| Bologna | 81.00 | 6.00 | 41.00 |
| Genoa | 501.00 | 34.00 | 4.50 |
| Sassuolo | 501.00 | 51.00 | 3.00 |
| Torino | 501.00 | 21.00 | 7.50 |
| Parma | 751.00 | 51.00 | 4.00 |
| Udinese | 751.00 | 29.00 | 6.00 |
| Cagilari | 1001.00 | 67.00 | 3.25 |
| Cremonese | 1501.00 | 151.00 | 1.61 |
| Pisa | 1501.00 | 151.00 | 1.72 |
Who are the favorites to win the 2025-26 Serie A Title?
Napoli
Napoli, the defending champions, are the favorites to win the 2025-26 Serie A title, with bookmakers offering an implied percentage of 38.2%. Last season, Antonio Conte's men displayed champion strength by clinching the Scudetto on the final day of Serie A, finishing on 82 points with 24 wins, 4 draws, and 10 losses. The club has kept Antonio Conte while strengthening his squad for the coming campaign. This revamped squad reflects Napoli's ambition to compete at the highest levels both domestically and in European competitions. With a blend of experienced internationals and emerging talents, they are poised for an exciting season ahead. Kevin De Bruyne is the headline arrival on a free transfer from Manchester City, while the club spent £21 million on PSV winger Noa Lang. Lorenzo Lucca also joined the club on loan with an obligation to buy from Udinese, while Dutch center-back Sam Beukema signed from Bologna on a five-year deal.
Napoli’s 2025/26 Squad
As of August 14, 2025, here is SSC Napoli's squad for the 2025/26 season, with several new signings and departures.
| Position | Player(s) |
|---|---|
| Goalkeepers | Vanja Milinković-Savić, Alex Meret, Nikita Contini |
| Defenders | Sam Beukema, Alessandro Buongiorno, Amir Rrahmani, Juan Jesus, Luca Marianucci, Alessandro Zanoli, Nosa Obaretin |
| Midfielders | Scott McTominay, Billy Gilmour, Frank Anguissa, Stanislav Lobotka, Kevin De Bruyne, Luis Hasa, Danilo Soddimo |
| Forwards | Romelu Lukaku, Noa Lang, Lorenzo Lucca, Matteo Politano, Giovanni Di Lorenzo |
Inter Milan
Inter Milan are the second favorite to lift the Serie A title, with bookmakers offering the Nerazzurri an implied percentage of 26.7%. Following a disappointing Champions League final result against PSG, the Champions League runners-up replaced Simone Inzaghi and appointed Parma boss Cristian Chivu as manager. Inter Milan has strengthened their squad by signing Croatian midfielder Petar Sučić from Dinamo Zagreb and Brazilian winger Luis Henrique from Olympique de Marseille. Following their elimination from the tournament and the conclusion of the 2024–25 season, Inter parted ways with Austrian striker Marko Arnautović after his contract expired. The Nerazzurri have consistently made the top 4 and have huge squad depth to chase a third Serie A title in four seasons.
Inter Milan’s 2025/26 squad
As of August 14, 2025, here is Inter Milan's squad for the 2025/26 season, with several new signings and departures.
| Position | Player(s) |
|---|---|
| Goalkeepers | Yann Sommer, Raffaele Di Gennaro, Matteo Cocchi |
| Defenders | Alessandro Bastoni, Stefan de Vrij, Francesco Acerbi, Benjamin Pavard, Denzel Dumfries, Matteo Darmian, Carlos Augusto, Yann Bisseck, Tiago Tomas Palacios, Matteo Cocchi |
| Midfielders | Nicolo Barella, Hakan Çalhanoğlu, Kristjan Asllani, Petar Sučić, Franco Carboni, Ebenezer Akinsanmiro |
| Forwards | Lautaro Martínez, Marcus Thuram, Ange-Yoan Bonny, Mehdi Taremi, Ademola Lookman |
Serie A Predictions
- Bet: Napoli to win the title for 2.62 odds
- Bet: Inter Milan to finish in the top four for 1.33 odds
