Kevin de Bruyne will return to the Etihad Stadium less than 3 months after leaving Manchester City when Napoli lands in Manchester for matchday one of the Champions League. Napoli has a perfect record in Serie A and sits atop the standings. Manchester City returned to their best in the domestic league with a 3-0 smashing of city rivals Manchester United. The Citizens are the favorites to win this game. City won the last two games between the two sides, beating Napoli with an aggregate score of 6-3 when the teams last met in the 2017-18 season.
Bet on Manchester City vs Napoli with Bet365
Manchester City vs Napoli Match Details
- Date: Thursday, September 18, 2025
- Time: 21:00 CEST
- Venue: Etihad Stadium, Manchester
Where to Watch Manchester City vs Napoli Live on TV or Stream
| Country | TV Channel/Stream |
|---|---|
| UK | TNT Sports |
| US | Paramount+, CBS Sports |
| Canada | DAZN |
| South Africa | Supersport |
Manchester City vs Napoli Match Preview
Manchester City form and statistics
Pep Guardiola's Manchester City has made a slow start to the English Premier League season, winning two and losing two. Although they thumped United in the Manchester derby last weekend, Manchester City will be looking to exorcise the demons of last season's Champions League run when they finished 22nd in the League phase before being knocked out by Real Madrid in the playoffs. Guardiola has a slew of absentees and may call up youngsters like Rico Lewis, Oscar Bobb, and others. Erling Haaland, who scored at the weekend, is poised to start as he continues to chase the UCL record of the fastest player to reach the 50-goal mark. The Norwegian striker is on 49 goals in 48 matches.
Manchester City possible starting lineup:
Donnarumma; Lewis, Dias, Guardiol, Ake, Rodri, Gonzalez, Savinho, Foden, Doku, Haaland
Bet on Manchester City vs Napoli with Bet365Napoli form and statistics
The Italian Champions have strengthened in the wake of securing another Serie A title. Former City player Kevin de Bruyne and ex-Manchester United striker Rasmus Hojlund have joined the Naples side and made a combined impact in the 3-1 victory over Fiorentina last weekend, with each player bagging a goal. Napoli will be making a Champions League return after missing out in the 2024-25 season.
Napoli possible starting lineup:
Milinkovic-Savic; Di Lorenzo, Beukema, Buongiorno, Spinazzola, Lobotka, Politano, Anguissa, De Bruyne, McTominay, Hojlund
Manchester City vs Napoli Match Prediction
The Citizens are clear favorites to get the 3 points here, according to the bookies. I agree with them. Despite the influence of De Bruyne and the red-hot form of Napoli, City have the depth to overcome their injured players and will run out winners here.
Manchester City vs Napoli Betting Odds
| Bookmakers | City to Win | Draw |
|---|---|---|
| Bet365 | 1.65 | 4.00 |
| 1xbet | 1.712 | 4.2 |
| Betway | 1.61 | 3.85 |


