Chicago Cubs vs San Diego Padres Prediction: Chicago Cubs to be the better team in this matchup

Chicago Cubs vs San Diego Padres: Prediction for the match on September 30, 2025

The Chicago Cubs will host the San Diego Padres at Wrigley Field on Tuesday to start the NL Wild Card Series. ABC will show the first pitch live. The Cubs are -115 on the moneyline, and the Padres are slightly behind at -104. The odds are in favor of San Diego on the run line (-1.5), and the total is seven runs. Late in the season, Chicago (92-70) lost six of seven games, but they saved face by sweeping the rival Cardinals over the weekend. San Diego (90-72) almost took the West from the Dodgers but fell short. Still, they come in hot, having won seven of their last eight games. Here at Telecomasia, we will preview this game and offer the best betting opportunities.

Chicago Cubs: Form and Statistics

Kyle Tucker has a .266 batting average, 25 doubles, four triples, 22 home runs, and 87 walks, which makes him a balanced hitter. He is 65th in home runs and 77th in RBIs in the majors.Nico Hoerner has the highest batting average for the Chicago team at.297. He isn't strong because he only hits 264 home runs, but he is consistent. Pete Crow-Armstrong hits.247 and adds the pop with 37 doubles, four triples, and 31 home runs. He comes into this game with a four-game hitting streak, having hit.294 with two home runs and five RBIs in his last five games. Seiya Suzuki is the engine that drives the lineup. He has 103 RBIs, which is the most on the Cubs, and he hasn't slowed down—he's had a hit in seven straight games and five home runs in his last ten games. Chicago came into this game after beating the Cardinals 2-0. Javier Assad pitched five and a third scoreless innings to close the door, and Suzuki hit a solo home run. The ball is now in Boyd's hands. The veteran lefty has a 3.21 ERA and a record of 14-8 in 31 games. He has pitched 179 2/3 innings and struck out 154 batters, keeping opponents to a.235 average. He has been dependable, making 17 quality starts and pitching at least five innings in 29 games. He has walked away eight times this year without giving up an earned run. Boyd has pitched against San Diego twice and only given up two runs in 11 1/3 innings..

Chicago Cubs: Team News

The Cubs are sixth in home runs (223), sixth in slugging (.430), and fifth in runs scored (793). They also get on base 32% of the time, which is good for 10th place in MLB. They still have one of the most balanced lineups in baseball, with a team average of.249 and just under eight strikeouts per game. The Padres have a .252 team average, which is seventh in the league, but they don't hit for power. They are 28th in home runs with 152 and 22nd in slugging with a.390 average

San Diego Padres: Form and Statistics

This is Nick Pivetta's 32nd start of the season for San Diego. The right-handed pitcher has a record of 13 wins and 5 losses, an ERA of 2.87, and 190 strikeouts in 181 2/3 innings. His WHIP is an elite .985, and opponents are only hitting.195 against him. He has been consistent all year, making 19 quality starts and pitching at least five innings in 26 games. He hasn't given up a single earned run seven times. In his last game against Milwaukee, he pitched 5 2/3 innings and gave up three runs on four hits. This will be another hard test. With 223 home runs, Chicago is sixth in that category. They are also sixth in slugging percentage (.430) and 11th in total hits with 1,371 on a .249 average. Pivetta has pitched against the Cubs before. This season, he pitched nine innings and gave up four runs on ten hits while striking out ten batters. The 32-year-old is ninth in ERA, fifth in WHIP, and sixteenth in strikeouts per nine innings among qualified pitchers.

San Diego Padres: Team News

Fernando Tatis Jr. is getting hot, hitting. 268 with 25 home runs, 27 doubles, and 89 walks. He has hit safely in eight straight games and has a .368 average over his last ten games, with three home runs. Manny Machado is the team's best power hitter and producer, with 27 home runs and 95 RBIs, which puts him in the top 40 in both categories in the league. Luis Arraez has a .292 batting average, which helps balance things out. Ryan O'Hearn adds to the mix with 17 home runs and a .281 average. But as a group, San Diego's power is behind. With 152 home runs, they are 28th, and with a slugging percentage of.390, they are 22nd. Their .252 team average is still the seventh-best in MLB, and their .321 on-base percentage is the ninth-best. They score 4.3 runs per game, which is 18th in the league.

Chicago Cubs vs San Diego Padres Betting Tips and Odds

• The Cubs have thrived as favorites this season. They’ve been in that spot 116 times and won 74 of them, a 63.8% clip. When the line sits at -115 or shorter, they’ve been even stronger, going 72-38. The moneyline gives them a 53.5% chance in this matchup.
• San Diego knows the other side of the story. The Padres have been underdogs 69 times and claimed 35 wins. When pegged at -104 or longer, they’ve gone 31-33. Oddsmakers put their chances at 51% here.
• Recent form tilts slightly toward Chicago. The Cubs are 4-2 when favored in their last 10 and have covered six of those contests. Six of those games also pushed past the run total.
• The Padres have been steady, too. As underdogs in three of their last 10, they went 2-1. They’ve split the totals at 4-6, but cashed six wins against the spread.

Chicago Cubs vs San Diego Padres Match Prediction 30 September 2025

The Padres finished the season strong, winning seven of their last eight games. Now, they have to play the Cubs on the road. San Diego had a hard time on the road, going 38-43. They were only able to win 23 of 29 games on the road. On the other hand, Chicago did well at Wrigley, going 50-31, including 46-24 as home favorites. The Padres also didn't do well against winning teams, going 24-26 against teams with a record above.540. Nick Pivetta is next. The right-handed pitcher had a 3.55 ERA and a 1.14 WHIP on the road, where he went 5-4. His trip to Wrigley in April was hard; he only pitched three innings and gave up six hits and three runs. The Cubs are the better team at this price because they have a strong home record and San Diego's road record is shaky.

Our match prediction is a moneyline result for the Chicago Cubs with odds at 1.86 on 1Xbet bookmaker.

Our betting tip is Over 7.0 runs with odds at 1.90 on Bet365 bookmaker.

Our final match prediction is A run in the 1st Inning (No) with odds at 1.62 on Betway bookmaker.