Chicago White Sox vs New York Yankees Prediction: The Yankees will overpower White Sox again

Here at Guaranteed Rate Field, the Chicago White Sox will take on the New York Yankees in Major League Baseball. This is the second game of a three-game series with the Yankees starting with a win. Can the Chicago White Sox, despite being heavily unfavoured even this series? Below, I will provide match analysis from a betting perspective and offer predictions. 

Chicago White Sox: Form and Statistics

The Chicago White Sox started this series on the negative end and will eye a win in this one. In the opener, this team scored four runs, all coming in the second inning when they turned the game to 4-4 before conceding six other runs. Meanwhile, that defeat extended Chicago White Sox’s losses to three having struggled in their series against the Kansas City Royals where they lost the final two games despite a 7-0 opening game win. Ahead of this game two, the Chicago White Sox record stands at 48-86 as they sit bottom of the American League standings. 

Chicago White Sox Team News and Lineup

The Chicago White Sox will send Yoendrys Gómez who will be making his fourth start this season on the mound. 

Chicago White Sox Predicted Lineup

Mike Tauchman (L) RF, Miguel Vargas (R) 1B, Kyle Teel (L) C, Lenyn Sosa (R) 2B, Andrew Benintendi (L) LF, Edgar Quero (S) DH, Curtis Mead (R) 3B, Brooks Baldwin (S) CF, Chase Meidroth (R) SS

New York Yankees: Form and Statistics

The New York Yankees continued their impressive record with a 6-run win in the opener. In the meantime, New York Yankees have won five consecutive games, sweeping the Washington Nationals in that run. Meanwhile, their recent series defeat came against the Boston Red Sox as they failed to win a single game. With a 74-60 record, New York Yankees sit third in the American East Division. 

New York Yankees Team News and Lineup

The New York Yankees are expected to send Carlos Rodón on the mound in this game two. Rodón has been impressive with his record standing at 14-7 this season. The American has a 3.24 average earned runs, 1.07 walks plus hits per inning pitched, and 172 strikeouts over 158 innings pitched. 

Aaron Judge has been crucial for the New York Yankees all season, and will be a player to watch. His batting average at .323, while he also leads in home runs (41) and runs batted in (95). 

New York Yankees Lineup

Trent Grisham (L) CF, Ben Rice (L) C, Aaron Judge (R) DH, Cody Bellinger (L) LF, Giancarlo Stanton (R) RF, Jazz Chisholm Jr. (L) 2B, Paul Goldschmidt (R) 1B, Ryan McMahon (L) 3B, Anthony Volpe (R) SS

Chicago White Sox vs New York Yankees Betting Tips & Odds

• The Chicago White Sox avoided a sweeping loss in each of their last three series prior to this. Meanwhile, this team also achieved this feat in their last series with the Yankees. Despite the bookies not backing the Yankees, they will still look to turn the tables with their moneyline set at 2.85 on Betway.
• The recent meetings between the Chicago White Sox and New York Yankees have ended with many runs. In their last five games together, the lowest number of runs was five, while we witnessed 14 runs in two games. This game has a potential of ending with at least eight runs with odds at 1.53.
• The New York Yankees have been better than the Chicago White Sox all season and are the favourites to win this game. Also, the New York Yankees have only lost once to the Chicago White Sox in their last six games. The moneyline odds is 1.40 on Bet365.

Chicago White Sox vs New York Yankees Match Prediction 30 August 2025

Despite the Chicago White Sox recent improvements, it is just clear the hosts are no match for the New York Yankees. All season, the New York Yankees have been impressive with a lot of top performances. Meanwhile, the Chicago White Sox do not look ready for this game after what I saw from them in the opener, especially considering the number of runs they conceded. Yet, I expect a better performance from the Chicago White Sox in this game two but with Yoendrys Gómez taking on the ball, my expectations do not look like the one that will materialise. With Carlos Rodón on the mound for the New York Yankees, I feel the visitors will have an easy path to victory. Also, the Yankees offense has been ruthless lately and with the Chicago White Sox looking lost, I do not see them containing the Yankees in the first inning. 

Our match prediction is a -1.5 handicap for the New York Yankees with odds at 1.76 on Bet365 bookmaker. 

Our betting tip is over 0.5 runs in the first inning with odds at 1.88 on 1Xbet bookmaker. 

Our final match prediction is a moneyline win for the New York Yankees and over 6.5 runs with odds at 1.83 on Betway bookmaker.