Detroit Tigers vs Cleveland Guardians Prediction: Cleveland Guardians to continue their unbeaten streak

Detroit Tigers vs Cleveland Guardians: Prediction for the match on September 17, 2025

In a three-game series at Comerica Park, the Cleveland Guardians (79-71) travel to Detroit to play the Tigers (85-66). These AL Central rivals are playing each other for the eighth time this season. Detroit is favored by the oddsmakers. Cleveland comes in as the Favourite, and the underdog are the favorites, giving -1.5 on the run line. Eight runs is the set total. We'll break down the best betting angles for this matchup, which is tense at the playoff level. Here at Telecomasia, we will preview this game and offer the best betting opportunities.

Detroit Tigers: Form and Statistics

Since June 1, the Tigers have had a losing record. They simply are not a good baseball club, and they are a lousy team even when Skubal isn't playing. This team's postseason chances are not looking good. This season, Detroit's hitters have been reliable. The Tigers are eighth in MLB, averaging 4.86 runs per game and a.420 slugging percentage. They have scored 729 runs, including 187 home runs and 232 doubles. With a.249 average and a.318 on-base percentage, the lineup has drawn 473 walks while striking out 1,323 times. Detroit's ERA and WHIP on the mound are 3.91 and 1.238, respectively. Their crew has issued 442 walks and struck out 1,264 batters. Overall, the opposition has scored 634 runs on 1,206 hits, including 174 home runs. Casey Mize receives the ball at start number 26. After 131 2/3 innings, he has a 3.83 ERA, 1.27 WHIP, and a record of 14-5. He struck out eight batters in six innings during a win at Yankee Stadium last week. Despite a 4.82 ERA and a strong 1.13 WHIP, he has a 5-1 record in his past seven outings. He has a 3.47 ERA and an 8-1 home record this season. He has a 2.30 ERA in three starts and a lifetime record of 1-1 against Cleveland.

Detroit Tigers: Team News

In partnership with the Michigan Miracle League, the Tigers held their annual Baseball Fantasy Camp Day for Kids. 50 children joined players Parker Meadows, Spencer Torkelson, and Zach McKinstry for a day of baseball and got to experience what it's like to be a Tiger. Riley Greene leads the offense with 34 home runs, 108 RBIs, and a.265 batting average. In the MLB, he ranks fifth in RBIs and ninth in home runs. Spencer Torkelson provides power, with 28 home runs and 26 doubles. He's also swinging well, hitting.316 over his last five games. Zach McKinstry's batting career includes 21 doubles, 11 triples, and 11 home runs, providing balance. 261.

Cleveland Guardians: Form and Statistics

The Guardians have the third best record in baseball since their 10-game losing streak. It's simple to figure out. They are making plays when it counts the most and squeezing by with wins. The Tigers have been playing losing baseball for the past two weeks, while the Guardians have all the momentum. The Guards extended their winning streak to five games with four extra base hits in the tenth inning, bringing their total to 11-6 in extra innings, the most in Major League Baseball. The Hillcats gave up a lot of runs last inning, but 2025 draft pick Nolan Schubart just turned a 96 MPH fastball into a solo home run that flew out of the ballpark in Columbia. With two games left, Cleveland and Texas are deadlocked for the last AL Wild Card slot. With nine wins in their past ten games and four straight victories, momentum is on their favor. Low-scoring games have also become the norm, with the Under hitting in six consecutive. With a 3-2 victory on Sunday, the Guardians completed a sweep of the White Sox. Bo Naylor, who went 2-for-3 with a double, a home run, a walk, and three RBIs, was the game's star. Jose Ramirez still leads the lineup. He has a.281 batting average, 77 RBIs, and 28 homers. Steven Kwan has 273 hits, 52 walks, and 26 doubles. Angel Martinez has 22 doubles and 11 home runs, and Kyle Manzardo has 26 home runs.

Cleveland Guardians: Team News

CJ Kayfus is eligible to represent Brazil in the World Baseball Classic. The Guardians' highly rated prospect and recent call-up is half Brazilian (by his mother's side). Joey Cantillo takes the ball on the mound. He has pitched 80 1/3 innings, struck out 10.3 per nine, and is 5-3 with a 3.36 ERA. In his most recent appearance, he tossed eight scoreless innings against Kansas City, which was an absolute masterpiece. In his previous seven starts, he has a 4-3 record, a 2.52 ERA, and a 1.17 WHIP. He is 3-1 on the road this season, having pitched 41 2/3 innings with a 3.02 ERA. In his single bullpen appearance against Detroit in May, he threw a clean inning and struck out one.

Detroit Tigers vs Cleveland Guardians Betting Tips and Odds

• With less innings this year, Emmanuel Clase’s arsenal from 2020-2025 is unbelievable. He has the highest rated arsenal of anyone over that stretch. In 2024, Clase posted 47 saves with a .61 ERA.
• MLB teams have on average 7.23 players with 1.5 fWAR or more as of today. The Detroit Tigers have 12, tied with the Toronto Blue Jays for the most in baseball.
• The Tigers have thrived as favorites this year, winning 63 of 104 games. When laying -144 or more, they’ve gone 43-20. For this matchup, the moneyline gives them a 59% chance to win.
• Cleveland has played the underdog role often, winning 37 of 82 times. At +120 or worse, they’ve taken 20 of 37. Their implied chance here sits at 45.5%.
• Recent form tells a mixed story. Detroit is just 2-4 in its last six games as a moneyline favorite. Across their last 10, they went 5-5 against the spread, but seven contests sailed over the total.
• The Guardians, meanwhile, are hot. They’ve gone 3-0 as underdogs in their last 10 and sit 8-2 against the spread. Low-scoring games have been the trend, hitting the under in eight of those 10.

Detroit Tigers vs Cleveland Guardian Match Prediction 17 September 2025

While the Cleveland Guardians are in excellent form following a sweep of the Chicago White Sox, I suspect they will suffer in this Tigers series. You may argue that the Detroit Tigers did not play their greatest game in Miami, but completing the series with a win is a significant momentum boost that will be noticeable in how they play in this game. 26-31 in the last 57 games. I'm so tired of hearing about how good the Tigers were in the final month of last season and the first three months of this season. While the Cleveland Guardians' offensive has been underwhelming, the Detroit Tigers' has also struggled. This should be a game in which both teams will be extremely cautious, with a win as the primary goal. I'm not convinced the tigers will recover from this. They've been 26-31 since July 9th. That is 22nd in the MLB. They are not good.

Our match prediction is a moneyline result for the Cleveland Guardians with odds at 2.25 on 1Xbet bookmaker.

Our betting tip is Over 8.0 runs with odds at 1.86 on Bet365 bookmaker.

Our final match prediction is +1.5 Cleveland Guardians with odds at 1.60 on Betway bookmaker.