Washington Nationals vs Chicago White Sox Prediction: Chicago White Sox to improve on their statement performance

Washington Nationals vs Chicago White Sox: Prediction for the match on September 27, 2025

Cade Cavalli gets the start for the Washington Nationals on Friday night at Nationals Park. Across the diamond, Colson Montgomery leads the Chicago White Sox. First pitch is set for 6:45 p.m. ET in the opener of a three-game set. The Nationals enter as favorites at -130 on the moneyline. The White Sox sit as underdogs at +110. Washington is also favored by -1.5 runs, while the total for the game is set at 8.5. Here at Telecomasia, we will preview this game and offer the best betting opportunities.

Washington Nationals: Form and Statistics

The Nationals are coming into this series with mixed results. They've lost 7 of their last 10 games, but they are on a one-game winning streak. They are 4-6 against the spread, with two covers in a row. The totals are even: four overs, five unders, and one push. However, both of their last two games have gone under. C.J. Abrams has the best batting average on the team at.259. He has gotten hits in two games in a row, but in the last five games, he has only hit.182. In that time, he hit two doubles, one home run, and drove in four runs. The real power source has been James Wood. He has 30 home runs and 92 RBIs, which puts him 25th in both categories in MLB. Wood has gotten hits in three games in a row and is hitting.278 in his last five games, with three home runs and a double. The Nationals beat the White Sox by scoring four runs in the middle of the week. Wood was the best player, hitting two home runs and driving in two runs. Andrew Alvarez started the game and pitched 4.1 innings without giving up a run or a hit.

Washington Nationals: Team News

Alex Clemmey has been named the Federal Baseball Washington Nationals Prospect of the Year. His impressive performance and dedication have set him apart in the farm system. The future looks bright for this rising star. Bob Carpenter bids farewell after 20 years as the voice of Nationals baseball leaving a legacy in the booth. The Nationals are hiring Red Sox Assistant GM Paul Toboni to run baseball operations.

Chicago White Sox: Form and Statistics

The 2025 regular season concludes with both Chicago teams showcasing their unique journeys. The Cubs make significant strides in their pursuit of a playoff spot, while the White Sox battle through challenges. Chicago has flashed occasional offense, like Montgomery’s two-run shot on Tuesday, but overall inconsistency at the plate and a shaky bullpen leave them vulnerable against a contender of this caliber. The Yankees rallied to beat the Chicago White Sox 3-2 Tuesday night, securing their eighth playoff appearance in nine seasons. The White Sox lost again on Thursday, which has been a big part of their season. They scored three runs, but the pitching staff gave up five. Michael Taylor hit a home run and drove in two runs, which gave the team a boost. Davis Martin, the starter, pitched for 4.1 innings and gave up six hits and three runs. Chicago's offense is ranked 28th in the league, and they only score 3.93 runs per game. Their pitching hasn't been much better, giving up 4.57 runs, which is 21st best. With 21 home runs, 72 RBIs, and a.259 average, Lenyn Sosa is in first place. He is 68th in the majors in home runs and 77th in RBIs. Miguel Vargas has also been steady. He has a .314 on-base percentage and is hitting.232 with 32 doubles, 15 homers, and 54 walks. Vargas has been hitting well lately, going 6 for 6 in his last 10 games with two doubles, a home run, and five RBIs.

Chicago White Sox: Team News

Chase Meidroth has a .257 average, 15 doubles, and five home runs. Colson Montgomery adds to the list with 19 home runs, 24 walks, and a.231 average. Yoendrys Gómez will pitch the ball. He has a 4.92 ERA and is 3-3, having lost his last three starts. He pitched 5.1 innings against the Padres last week, giving up six hits and three runs.

Washington Nationals vs Chicago White Fox Betting Tips and Odds

• This year, the Nationals haven't done well as favorites. In that role, they've only won six of 18 games, which is a 33.3% rate. They are only 2-8 when the odds are -130 or lower. The moneyline on Friday says they have a 56.5% chance of winning.
• Washington's offense is 20th in the league, averaging 4.23 runs per game. Their pitching staff, on the other hand, is 29th in the league, giving up 5.51 runs per game.
• Chicago's record as an underdog is only a little bit better. The White Sox have won 57 of the 156 games they were not expected to win, which is 36.5%. Their implied chance of winning is 47.6% at +110.
• Recent form doesn't help that much. Washington hasn't been favored in its last ten games, and it has a 4-6 record against the spread. They've gone over in only four of those games.
• The White Sox haven't done any better. In their last ten games, they are 1-8 as underdogs. They have a 3-7 record against the spread, but they have covered the spread five times in that time.

Washington Nationals vs Chicago White Sox Match Prediction 27 September 2025

The Nationals could get off to a good start in this series. Cade Cavalli gets the ball, and his form is what makes the difference. In his last game, he didn't give up any runs. He now has to play against the White Sox, who have one of the weakest lineups in the league. Cavalli has been even better at Nationals Park. In four starts at home this season, the 27-year-old has a 2.11 ERA and keeps hitters to a .218 average. This will be his tenth start of the year, and the stats show that he's ready to take over again. On the other hand, Yoendrys Gómez has been helpful but not very good. He should give up three or four runs before the bullpen gives up a few more. That should be enough to help Washington win the contest. The moneyline says the Nationals will win. Trends in scoring also point to a low total. The White Sox are 24th in runs scored this month, and Washington has had the same problems at the plate. The under seems like the safer bet because neither team is going to the playoffs.

Our match prediction is a moneyline result for the Chicago White Sox with odds at 1.76 on 1Xbet bookmaker.

Our betting tip is Over 8.5 runs with odds at 1.83 on Bet365 bookmaker.

Our final match prediction is +1.5 Chicago White Sox with odds at 1.60 on Betway bookmaker.