Washington Nationals vs Chicago White Sox Prediction: Can Chicago White Sox get back to winning ways?

Washington Nationals vs Chicago White Sox: Prediction for the match on September 28, 2025

The Washington Nationals (65–95) enter Sunday’s matchup as slight moneyline favorites at -111. First pitch is set for 3:05 p.m. ET, with James Wood and the Nationals facing Chicago starter Shane Smith. Oddsmakers list Washington at -112, while the White Sox (59–101) sit at -104. On the run line, Chicago is favored at -1.5. The game carries a total of 8.5 runs. Here at Telecomasia, we will preview this game and offer the best betting opportunities.

Washington Nationals: Form and Statistics

The Nationals' offense is 20th in MLB, with 681 runs scored in 4.3 games. They are 25th in home runs with 158 and 21st in batting average with.243. Their lineup strikes out 8.3 times per game, which puts them in 13th place. Washington has trouble on the mound. The pitching staff only gets 7.9 strikeouts every nine innings, which puts them in 26th place. Their team has a 5.34 ERA, which is 29th in all of baseball. C.J. Abrams is the best hitter, with a.260 average, 19 home runs, and 60 RBIs. He comes into this game with a three-game hitting streak, but in his last five games, he has only hit .182 with a double, a home run, a walk, and two RBIs. He is 93rd in home runs and 129th in RBIs in all of MLB this season.

Washington Nationals: Team News

James Wood has been the team's big hitter. He has a .254 batting average, which is the best on the team, and 30 home runs and 92 RBIs, which is also the best on the team. That many home runs puts them 28th in the league, and that many RBIs puts them 26th. Luis Garcia hits. and gives steady numbers. 255 with 28 doubles, a triple, 16 home runs, and 26 walks. Josh Bell brings experience to the lineup by hitting. 238 with 15 doubles, a triple, 22 home runs, and 56 walks. He has hits in two games in a row and is hitting well in his last five games, with a. 429 with a double, two home runs, a walk, and two runs batted in.

Chicago White Sox: Form and Statistics

Miguel Vargas has a.233 average, 32 doubles, two triples, 15 home runs, and 54 walks. He has hit in seven straight games, with a batting average of. In his last 10 games, he has 257 hits, including a double, a home run, four walks, and five RBIs. His home run total is 140th among MLB hitters, and his RBIs are 134th. The team has been on fire thanks to Lenyn Sosa. With 22 home runs, 75 RBIs, and a.263 batting average, he is the best player in Chicago. He is 65th in home runs and 66th in RBIs in the majors. Chase Meidroth has stayed steady with a .257 average, 15 doubles, five home runs, and 45 walks. Colson Montgomery also adds power by hitting. 231 hits, eight doubles, a triple, 20 home runs, and 24 walks.

Chicago White Sox: Team News

The White Sox have had a hard time hitting as a team. They have 634 runs, which is 27th in the MLB, and they only score four runs per game. They have 160 home runs, which puts them in 23rd place, and their team batting average is.232, which puts them in 27th place. The Chicago lineup strikes out 8.4 times a game, which is 16th. The pitching staff has an 8.1 K/9 rate, which puts them 22nd in the league. They have a combined ERA of 4.30, which puts them in 20th place overall. Smith is making his 29th start of the year with a record of 6–8.

Washington Nationals vs Chicago White Sox Betting Tips and Odds

• The Nationals have struggled when favored this season. Out of 19 games, they’ve won only six, a rate of 31.6%. In 17 matchups with odds of -112 or shorter, they sit at 5–12. Based on the moneyline, their implied chance of winning here is 52.8%.
• Chicago’s path hasn’t been much brighter. The White Sox have entered 157 games as underdogs and managed to win 58, or 36.9%. When priced at -104 or longer, they hold a 57–98 record. Oddsmakers give them a 51% shot in this matchup.
• Form over the last 10 games adds more context. Washington has been favored just once in that stretch, and they lost. They’ve gone 4–6 against the spread and hit the over in four of those contests.
• Chicago has played all 10 games as an underdog, winning only two. Their record against the spread stands at 5–5, with four games finishing over the total.

Washington Nationals vs Chicago White Sox Match Prediction 28 September 2025

The Nationals have a chance to get off to a good start in this series. Cade Cavalli takes the ball, and his form is what makes the difference. He didn't give up a single run in his last game. Now he has to face a White Sox lineup that is one of the weakest in the league. At Nationals Park, Cavalli has been even more on point. The 27-year-old has a 2.11 ERA and keeps hitters to a .218 average in four starts at home this season. This will be his tenth start of the year, and the numbers show that he's ready to take over again. Yoendrys Gómez, on the other hand, has been useful but not very good. Before the bullpen gives up a couple more runs, he should give up three or four. That should be enough to make the contest go Washington's way. The moneyline says the Nationals will win. Trends in scoring also point to a low total. This month, the White Sox are 24th in runs scored, and Washington has had similar problems at the plate. Since neither team is in the running for the playoffs anymore, the under seems like the safer bet.

Our match prediction is a moneyline result for the Chicago White Sox with odds at 1.90 on 1Xbet bookmaker.

Our betting tip is Over 8.5 runs with odds at 1.86 on Bet365 bookmaker.

Our final match prediction is -1.5 Chicago White Sox with odds at 2.20 on Betway bookmaker.