Estudiantes vs Flamengo Prediction: Tricolor aim to overturn deficit in La Plata

Estudiantes vs Flamengo: Prediction and odds on the Match on 26 September 2025

The second leg of this decisive Copa Libertadores 2025 quarterfinal heads to Estudiantes’ fortress, where Eduardo Dominguez's side must give all they can to overturn Flamengo’s 2-1 first-leg advantage from the Maracana. Flamengo struck early through Pedro and Giorian Varela, only for Perreira to score in his own net in the late minutes of the game, setting up a tense decider in the return leg.

The Brazilians, who advanced past Internacional 3-0 on aggregate in the round of 16 after finishing second in Group C, are unbeaten in their last 12 games across all competitions and sit atop the Brasileiro Serie A table. Estudiantes, who finished top of Group A before narrowly escaping Cerro Porteno in the round of 16, have lost three of their last five games overall. 

Controversy lingers as Gonzalo Plata’s red card in the first leg was overturned, and he is now free to face Estudiantes in the return leg, boosting Flamengo’s options. Expect drama and goals from this encounter. Check the team conditions! Several betting options are available.

Estudiantes: form and statistics

Form in all competitions: WLLLW

The Pincha under manager Eduardo Dominguez finished top in Group A with four wins and two losses from a total of six group games played. They scored the most goals in Group A with 11 goals to the good and just conceded 5, which happens to be the fewest goals conceded in the group. They secured a straight qualification to the round of 16, where they advanced to the quarterfinals via a narrow 1-0 aggregate win over Cerro Porteño. They faced a little setback in the first leg of the quarterfinals against Flamengo, where they suffered a 2-1 defeat. Early goals from Pedro and Varela gave Flamengo the early lead, until Estudiantes managed to pull one back courtesy of an own goal by Pereira.

In the Argentine Liga Profesional de Fútbol, Estudiantes is thriving with 5 wins and four losses from the nine league games played, complemented by their narrow 1-0 win over Defensa y Justicia over the weekend. They remain firm in third position, even with the fact that they’ve only won two of their last five league games. 

Estudiantes: Lineup

Guido Carrillo will lead the line as he has been doing. Dominguez prefers to use a single man upfront, and Carrillo is just the best man for this level of game. No suspensions for Eduardo to worry about, only a few injuries here and there. 

Player to watch out for: Guido Carrillo

The Veteran striker leads the team's attack, and he has scored two goals for Estudiantes in the Copa Libertadores. We believe he should get a goal in this game or cause trouble with his aerial power.

🔖 Estudiantes probable starting lineup (4-2-3-1)

Fernando Muslera – Roman Gomez, Nunez, Facundo Rodriguez, Santiago Arzamendia, – Amondarain, Ezequiel Povi – Santiago Ascacibar, Cristian Medina, Facundo Farias – Guido Carrillo

⛔️ Out: Edwin Cetre, Pirez, Eric Meza (injured). 

👤 Head coach: Eduardo Dominguez

Flamengo: form and statistics

Form in all competitions: DWWDW

Flamengo regained their lead at the top of the Brazilian league table after their prestigious run in the Club World Cup. Felipe Luis’ boys hold a slim lead at the top of the Brasileiro with a single point margin above second-place Cruzeiro. Flamengo is also unbeaten in their last 12 games across all competitions, with their most recent league game against Vauco ending in a 1-1 draw.

Flamengo had a tough time in Copa Libertadores Group C, finishing second place in a group where all three top finishers had the same number of points (11). They finished in second place, courtesy of their goal difference. They dismantled Internacional in the round of 16 by a 3-0 aggregate score, showcasing their strength. Early goals from Pedro and Varela before the 10th minute of the first half put the boys ahead in the first leg before Estudiantes pulled one back in the last minute of the game. With a slim advantage, Felipe Luis must find his way to the semifinals of the Copa Libertadores after being eliminated at this stage last year.

Flamengo Probable Lineup

Former Atletico-Madrid and Chelsea left-back Felipe Luis has been incredible since joining Flamengo, and he will be hoping to take his team through to the semifinals of the Copa Libertadores. Ayrton Lucas has been performing well, so he could keep his place in the starting eleven. Gonzalo Plata’s red card in the first leg was overturned, and he is now free to face Estudiantes in the return leg, boosting Flamengo’s options.

Player to watch out for: Giorgian De Arrascaeta

Giorgian De Arrascaeta is the team's current top scorer with a total of 13 goals in the league and two goals in the Copa Libertadores. He is currently valued at 14.5M Euros, and he is known for his high pressing and playmaking abilities. 

🔖Flamengo starting lineup (4-2-3-1)

Rossi – Guillermo Varela Léo Ortiz, Léo Pereira, Ayrton Lucas– de la Cruz, Saul Niguez – Gonzalo Plata, Giorgian De Arrascaeta, Samuel Lino – Pedro

⛔️ Out: Erick Pulgar, Michael, Jorginho, Bruno Henrique (injured). 

👤Head Coach: Filipe Luís

Estudiantes vs Flamengo: head to head statistics

This is the second meeting between the teams. Flamengo won the first leg encounter by a 2-1 scoreline.

Estudiantes vs Flamengo: Betting Tips & Odds

• No losses for Flamengo in their last 11 games across all competitions, and the option for Flamengo to win this game is offered on the BetWay bookmaker website for odds of 2.18;
• Flamengo has scored first in their last 10 games, and the option for Flamengo to score first is offered on the Bet365 bookmaker website for odds of 1.84;
• Flamengo has won the first half in 5 of their last 7 games across all competitions, and this option is offered in the 1xBet bookmaker at 2.88 odds;

Estudiantes vs Flamengo match prediction 26 September 2025

Estudiantes' home fortress and desperation should yield an early push for goals, but Flamengo’s quality, supported by Plata’s return, should give them an edge and help them strike decisively in counterattacks. Estudiantes will go all out for the win, but we do not see Flamengo losing this game. I believe Flamengo will make it to the semifinals. 

Our match prediction is a total of over 4 corners for Flamengo for a coefficient of 1.66 in the 1xBet bookmaker.

Our betting tip on the match is a Flamengo win, for a coefficient of 2.14 in the Betway bookmaker.

Lastly, a both teams to score for 2.02 odds in the Bet365 bookmaker.