Palmeiras vs River Plate Prediction: Millionaires know how to win in Sao Paulo

Palmeiras vs River Plate: Prediction and odds on the Match on 25 September 2025

River Plate, down 1-2 at Monumental, will play Palmeiras in the second leg of the Copa Libertadores quarter-finals. Palmeiras are on the verge of the Copa Libertadores semi-finals. Seven days ago, they beat River Plate at a packed Monumental 2-1 and have a good lead ahead of the second leg at their stadium in front of all 45,000 fans, dressed in green and white. Both teams rested their starters over the weekend, with Verdao easily defeating Fortaleza 4-1, while Atletico defeated Marcelo Gallardo's Millionaires in Tucuman (0-2) in the ninth round of the Clausura. The victory of the visitors from Buenos Aires by a goal difference takes the two-legged tie into a penalty shootout.

Palmeiras: form and statistics

Form in all competitions: WWWDW

Palmeiras players recently won the South American championship twice in a row, and in the meantime, this team have also managed to win the Brazilian championship. In the first match of the Copa Libertadores quarterfinals, this team played a great match and managed to win a very difficult away match against River Plate, which ended with a score of 1:2.As for the Brazilian championship, this team are currently in third place in the standings, two points behind first-place Flamengo, who also have a match in hand. Palmeiras are undefeated at home in the last five matches, winning four and drawing one match.

Palmeiras: Lineup

The Portuguese expert is expected to play with the same line-up tonight (02.30) as he did seven days ago at the Monumental. Right-back Kelven's playing time is questionable, but his recovery is going well, so he is expected to be ready. Victor Roque and Flaco Lopez will be in Verdaas' attack, while Felipe Anderson and Andreas Pereira will be in the back. Rafael Veiga is waiting for a place on the bench. He has not been the standard creator in the midfield in recent years. Only striker Paulinho is out of action, as he is facing a longer break after surgery.

🔖 Palmeiras probable starting lineup (4-4-2)

Weverton - J. Piquerez, Murilo, G. Gómez, Khellven - A. Moreno , Lucas Evangelista , Felipe Anderson, J. López - Andreas Pereira, Vitor Roque

⛔️ Out: Paulinho (injured).

👤 Head coach: Abel Ferreira

River Plate: form and statistics

Form in all competitions: LLWWD

Marcelo Gallardo must play more offensively and more aggressively than last week. Palmeiras crushed the hosts in the first 45 minutes, scoring two goals, but River played better in the second half, reducing the lead and even having chances to equalize. Still, the score remained 1:2. In recent years, River Plate players have failed to reach the final of the Copa Libertadores, and this could very well be the case this time. In the derby match of the quarter-final clashes, this team was defeated at home by Palmeiras, with a score of 1:2, so it is evident that Marcelo Gallardo's team needs a triumph on a very difficult away match to advance. By the way, if we look at the Brazilian Serie A, this team are currently in second place in the table, with a point gap compared to the first-placed Riestra.

River Plate: Lineup

Juan Quintero could get a chance from the start. Forward Sebastián Driusi is injured and has been ruled out for the second leg. Salas will be the most forward in the striker position, while Galopo and Castaño will threaten from the wings, while the "ten" is reserved for veteran Nacho Fernandez. Collidio and Colombian Miguel Borja will seek a chance from the bench.

🔖 River Plate probable starting lineup (4-3-1-2)

F. Armani - L. Rivero, J. Portillo, P. Díaz , E. Pérez - M. Acuña, G. Montiel, K. Castaño - I. Fernández - Colidio M. Salas

 ⛔️ Out: P. Martinez, M. Meza, G. Pezzella, A. Ruberto (injured).

👤 Head coach: Marcelo Callardo

Palmeiras vs River Plate: head to head statistics

These teams played nine matches so far in all competitions. Palmeiras are better team with four wins, River Plate have two wins, and three matches ended in a draw.

Palmeiras vs River Plate: Betting Tips & Odds

• Palmeiras won in their last 3 games across all competitions, and the option for Palmeiras to win this game is offered on the BetWay bookmaker website for odds of 1.75;
• Palmeiras have scored over 1.5 goals in 4 of their last 5 matches, and the option for Palmeiras to score over 1.5 goals is offered on the Bet365 bookmaker website for odds of 2.07;
• 7 of their 9 matches ended with more than 2.5 goals, and this option is offered in the 1xBet bookmaker at 2.3 odds;

Palmeiras vs River Plate match prediction 25 September 2025

River knows how to win in Sao Paulo. Four years ago, they beat the hosts 2-0 in the second leg of the Copa Libertadores semi-final, but were eliminated after being crushed at the Monumental (0-3). The winner of this tie will go to the better team from the Sao Paulo-LDU Quito duel. The Ecuadorian giants are closer to the semi-finals after winning 2-0 at home before the second leg the following night at Morumbi. I believe that Marcelo Gallardo's men have little choice but to go all out against Palmeiras, and it could very well happen that this team avoids defeat on the road against the Brazilian team. However, we can expect a great match with goals on both ends.

Our match prediction is over 2.5 goals for a coefficient of 2.3 in the 1xBet bookmaker.

Our betting tip is BTTS for a coefficient of 2.15 in the Betway bookmaker.

Lastly, W1 and over 2.5  for 3.2 odds in the Bet365 bookmaker.