Fluminense vs Lanus Prediction for the Match on September 24, 2025

Fluminense vs Lanus: Prediction and odds on the Match on 24 September 2025

Round of 16 second leg of the Copa Sudamericana quarterfinals sees Fluminense host Lanus at the iconic Maracana, with the Brazilian side needing to overturn a 0-1 away deficit from the first leg at Estadio Ciudad de Lanus while also leveraging on their home advantage. The Big Flu, sitting 8th in the Brasileirão with 9 wins, 8 draws, and 9 losses so far, narrowly escaped with a 0-1 victory in their last league game against Vitoria.  

Lanús, with a strong grip in their last three, advanced past Central Cordoba by penalties after an aggregate 1-1 draw across both legs. Fluminense, on the other hand, had a smooth sailing in the knockout stages after defeating America by a 4-1 aggregate score to secure their place in the Quarterfinals of the Sudamericana. 

Lanus pulled off a dramatic 1-0 home win in the first leg thanks to a 89th-minute strike from Marcelino Moreno. Fluminense’s attack should shine at home, where they’ve won 3 of 5 recent matches. We envisage a comeback victory for Fluminense. Check the team conditions! Several betting options are available.

Fluminense: form and statistics

Form in all competitions: WLLWD

The Big Flu finally won a game in their last league game against Vitoria after two games without a victory. It was a struggle for Fluminense in that game after Hercules’ goal in the 37th minute, but they prevailed regardless.

Fluminense aim for a positive outcome in the South American competition, where they last featured in 2022. They’ve also been poor in their last five games across all competitions, with only two wins in their last five. Their journey in the Copa Sudamericana began with a top position in Group F, where they won four games, drew one, and lost one from the six group games. They then faced America in the round of 16, where they secured a 4-1 aggregate score, 1-2 in the first leg and 2-0 in the return leg. The first leg against Lanus was a tough one; both teams came all out for the victory, but Lanus emerged victorious, all thanks to a late-minute goal from Lanus’ Moreno. Their home form is quite impressive with three wins in their last five games at the Maracana, but the tides have to be different at the Maracana. 

Fluminense Lineup

Renato Gaúcho is expected to field a potent attack at home, with no major injury concerns beyond long-term absentees like Ganso and Samuel Xavier. Renato rested some players in their game against Vitoria for this encounter. This illustrates the significance of this game in the broader context. He will field his regular 4-2-3-1 formation with Cano spearheading the attack.

Player to watch out for: German Cano

Argentine-born German Cano is the man to look out for in Wednesday’s clash. He has scored three goals for Flu in the Copa Sudamericana, and he will be aiming to increase his tally as they head into Wednesday’s clash.

🔖Fluminense starting lineup (4-2-3-1)

Fábio – Julio Fidelis, Thiago Silva, Fuentes, Renê – Martinelli, Hércules, – Nonato, Moreno, Lima, — Cano

⛔️Out: Samuel Xavier (injured)

👤 Head Coach: Renato Gaúcho

Lanus: form and statistics

Form in all competitions: WWWLL

Lanús is hoping to recreate their campaign in last year’s Copa Sudamericana, where they made it to the semi-finals but eventually got knocked out by Cruzeiro by a single goal margin in the semifinals. This season, Lanús has enjoyed a solid campaign in the Copa Sudamericana so far, finishing top of Group G with an unbeaten run. They recorded three wins and three draws, scoring nine goals and conceding just four along the way. In the Round of 16, the Granate faced Central Córdoba and looked in danger after losing the first leg 1-0. But they fought back with a 1-0 win in the return leg before winning in the penalty shootout to secure back-to-back quarterfinal appearances.

Now, they are one step closer to securing back-to-back semifinal qualifications to the Copa Sudamericana after their narrow 1-0 victory over Fluminense in the first leg. Marcelino Moreno’s 89th-minute strike was the difference between the two teams. 

Domestically, Lanús sits 4th in Liga Profesional de Fútbol Group B, recently defeating Platense 2-1, now making it three wins in a row for Granate. With this victory on their shoulders, they’ll head into the return leg of the Sudamericana quarterfinals determined to push harder and earn a spot in the semifinals for the second time in a row.

Lanus Lineup

Coach Mauricio has a big problem on his shoulders, and it's on his long list of injuries. Pellegrino is likely to proceed with the typical 4-2-3-1 formation, with the key elements being a tight midfield and quick attacks down the flanks. His attack will be led by Walter Bou, who scored the winning goal in their last league game against Independiente Rivadavia. 

Player to watch out for: Rodrigo Castillo

26-year-old Rodrigo Castillo has been in incredible form for Lanus this season, with four league goals to his name already. 

🔖 Lanus starting lineup (4-2-3-1)

Losada – Morgantini, Izquierdoz, Munoz, Marcich – Medina, Cardozo – Salvio, Segovia, Moreno – Castillo

⛔️ Out: De Jesus, Loaiza, Ortellado, Pena Biafore, Carrera, Luciano Romero,Lautaro Morales, Edgardo Ramirez, Franco Watson ( injured)

👤 Head coach: Mauricio Pellegrino

Fluminense vs Lanus: head to head statistics

This is the second meeting between the teams, with Lanus winning, and we are more than sure of a cracker here.

Fluminense vs Lanus: Betting Tips & Odds

• Less than 2.5 goals in Lanus’s last 7 games, and the option for a less than 2.5 goal here is offered on the 1xBet bookmaker website for odds of 1.58;
• Less than 10.5 corners in 4 of Fluminense's last 5 games, and this option is available on the Betway bookmaker website at 1.42 odds;
• Three consecutive wins for Lanus in their last three league games, and this option is available on the 1xBet bookmaker website at 6.40 odds;
• Some experts believe that Fluminense will win, and this option is offered in the Bet365 bookmaker at 1.63 odds;

Fluminense vs Lanus match prediction 24 September 2025

Fluminense are no strangers to the big stage, having built their reputation in the prestigious Copa Libertadores. But after a dip in form last season, they now find themselves competing in the Copa Sudamericana for the first time since 2022. For Lanús, this competition has been their territory; they’ve been consistent contenders, though their unbeaten run this year was finally broken in the Round of 16 against Central Córdoba.

With the Maracanã behind them and a one-goal deficit to erase, Fluminense’s superior continental form should overwhelm Lanus’s away woes. Expect Cano to strike early, leading to a multi-goal response while Lanus sits deep in their own half. We see a very tight game, with Fluminense advancing to the next round. 

Our match prediction is a total of over 2.5 corners for Lanus for a coefficient of 1.68 in the 1xBet bookmaker.

Our betting tip on the match is a win or draw for Flu, and a total of under 2.5 goals for a coefficient of 1.78 in the Betway bookmaker.

Lastly, a first-half draw for 1.98 odds in the Bet365 bookmaker.