U. De Chile vs Alianza Lima Prediction: U. De Chile are a slight favorite

U. De Chile vs Alianza Lima: Prediction and odds on the Match on 26 September 2025

The match between Universidad from Chile and Alianza from Lima, which is scheduled for tonight at the Estadio Nacional Julio Martínez Prádanos stadium in Santiago de Chile, the capital of Chile, concludes the quarter-finals of the Copa Sudamericana for this season. This is one of the most uncertain duels of the quarterfinals, the result from the first match is 0-0, and everything is open for both teams. In the first match, both teams had chances, but Alianza Lima can be more satisfied with the result as they were playing with a player less from the 64th minute, when C. Zambrano was sent off. We can expect a difficult match with a lot of fight in this duel, as big stakes are in play.

U.De Chile: form and statistics

Form in all competitions: DWLDL

Universidad de Chile arrived in Lima in high spirits, and they showed it in the field, but failed to gain an advantage before this match at home. The Blues won the Chilean Super Cup after a convincing 3-0 win over Colo Colo, boosting the confidence of Gustavo Alvarez's team, but it’s their only win in their last 5 matches in all competitions. They also advanced to the quarterfinals of the competition after CONMEBOL expelled Independiente de Avellaneda for incidents at their stadium in the round of 16. Despite their motivation, the popular U. De Chile will not be able to count on important players such as Israel Poblete, Nicolas Ramirez, Marcelo Diaz and Lucas Di Jory, who are regular starters and are out through injury. These absences will force a change in the starting lineup. However, coach Gustavo Alvarez will be able to count on some important players, such as midfielder Sergio Peña, who is in excellent form, and defender Gianfranco Chavez. U.De Chile lost in the last match in this stadium against A. Italiano in the domestic championship.

U.De Chile Lineup

In the first match in Peru, Gustavo Alvarez played in 3-5-2 formation, and it's expected that he will use the same in this match. During the recent training sessions he almost the same lineup, so probably he will play with the same team with very few changes.

U.De Chile starting lineup (3-5-2)

Gabriel Castellón (GK) - Fabián Hormazabal, Franco Calderón, Matías Zaldivia - Maximiliano Guerrero, Sebastián Rodríguez, Charles Aránguiz, Matías Sepúlveda, Javier Altamirano - Lucas Assadi, Nicolás Guerra.

⛔️Out: Israel Poblete, Nicolas Ramirez, Marcelo Diaz and Lucas Di Jory

👤 Head Coach: Gustavo Alvarez

Alianza Lima: form and statistics

Form in all competitions: WDLDW

Alianza Lima comes into the match in fifth place in the Peruvian championship, showing a solid campaign, although with visible oscillations in recent matches. The team led by Nestor Gorosito will try to use the experience and advance to the semifinals. Alianza Lima, which previously eliminated Universidad Católica from Ecuador and Gremio, are looking to continue their journey towards the semi-finals after several years of absence from the decisive stages of a continental competition. Since the start of this season, the team from Lima have played 44 matches, scoring 60 goals and conceding 39, which shows a productive attack, but with some defensive weakness. In the last three matches away from home, they have recorded two victories, against Ayacucho and U. Catolica, and drawn in the derby against U. De Deportes.

Alianza Lima Lineup

Coach Gustavo Zapata will have Pedro Aquino, a recent signing from Santos Laguna, at his disposal and should be in the starting lineup. However, some absences could negatively affect the team, such as C. Zambrano, who is suspended for a red card in the previous match in this competition, as well as Kevin Quevedo and Garces Mori.

Alianza Lima starting lineup (4-1-4-1)

Guillermo Viscarra (GK) - Guillermo Enrique, Gianfranco Chávez, Renzo Garcés, Miguel Trauco - Alessandro Burlamaqui - Fernando Gaibor, Sergio Peña, Eryc Castillo, Alan Cantero - Hernán Barcos

⛔️Out: IC. Zambrano, Kevin Quevedo, Garces Mori

👤Head Coach: Gustavo Zapata

U. De Chile vs Alianza Lima: head to head statistics

In the recent history of head-to-head matches between these teams, before the match from last week which ended in a goalless draw, there has been a 2-2 draw and a narrow victory for Universidad de Chile. Both matches were played in the group stage of the 2010 Copa Libertadores.

U. De Chile vs Alianza Lima: Betting Tips & Odds

• Under 2.5 goals in 3 of U. De Chile last 5meetings, and the option for under 2.5 goal here is offered on the 1xBet bookmaker website for odds of 1.67;
• A. Lima scored a goal in 4 of their last 5 away matches, and this option is offered on the Bet365 bookmaker website for odds of 1.58;
• U. De Chile won in 3 of their last 5 matches at home, and this option is offered on the Betway bookmaker website for odds of 1.85

U. De Chile vs Alianza Lima match prediction 26 September 2025

Only one goal can decide the winner and the last team of the semifinals, so I think that both teams will take defensive approach in this match. The pressure is huge, the stakes are big, but in my opinion, considering everything we saw in the first match U. de Chile are a slight favorite, and will use the support from the fans to win this match. I think it will be close match, with little excitement and chances but huge fight in the middle of the field.

Our match prediction is W1 for a coefficient of 1.85 in the 1xBet bookmaker.

Our betting tip on the match is HT-Draw, for a coefficient of 2.08 in the Betway bookmaker.

Lastly, correct score 1:0 for 6.5 odds in the Bet365 bookmaker.