Extremadura vs Sevilla Prediction: Sevilla must win!

Extremedura vs Sevilla Match Prediction 04 December 2025

A place in the third round of the Copa del Rey will be at stake when Extremadura hosts Sevilla at the Francisco de la Hera stadium on Thursday, December 4, 2025. This is no easy match for Sevilla, who are big favorites. They were defeated and embarrassed in the city derby last weekend and now need a convincing win to restore their confidence.

Extremadura: Form and Statistics

Extremadura play in the Segunda Federacion, one rung below Sevilla's reserve team, and even so, they are coming off two consecutive defeats without a win in their last three games. Extremadura were at their best when they demolished Las Palmas 3-1 in the previous round, with Marco, Imanol Barace, and second-half substitute Alfredo Sualdea scoring for the home side. Coach Cisqui could field a line-up similar to the one that brought victory last time in this competition, with Maikel Villajos and Marco in the attacking pairing. It is worth mentioning that the predecessors of the club UD Extremadura played against Sevilla several times, and their last meeting was a friendly match in August 2019.

Extremadura lineup

🔖 Extremadura Predicted Lineup (4-3-3): Rodriguez - Hurtado, Cano, Cordero, Tala - Callejon, Zarfino, Diaz - Barace, Manchon, Sualdea

👤 Head Coach: Juan Sabas

⛔ Out: /

Seville: Form and Statistics

Betis won the city derby against Sevilla 2-0 in the 14th round of the Spanish Primera, and finished in fifth place. The scorers for Betis were Pablo Fornals in the 54th minute and Sergi Altimira in the 69th minute. Sevilla ended the game with 10 men on the field after Isaac Romero received a straight red card in the 84th minute. The match was briefly stopped in the 88th minute due to disturbances caused by Sevilla fans. Although Sevilla are currently going through a difficult period, it is a first division team that should secure a fairly convincing victory against a four-division opponent. Sevilla have problems on and off the field, and the main concerns for the manager are with injuries before this game, but as a first league team, they should be ahead, given the difference in quality between these teams. Stopper Marcao picked up another injury in the recent Sevilla derby and will not be available for this match, as will Tanguy Nianzou, Adnan Januzaj, Gabriel Suazo, and Ruben Vargas.

Seville lineup

🔖 Sevilla Predicted Lineup (4-3-3): Nyland - Juanlu, Castrin, Salas, Oso - Bueno, Gudelj, Jordan - Sierra, Alfon, Sanchez

👤 Head Coach: Matias Almeyda

⛔ Out: Marcao, Tanguy Nianzou, Adnan Januzaj, Gabriel Suazo, and Ruben Vargas

Extremadura vs Sevilla Head-to-Head Statistics

This will be the first meeting between these teams, which is not surprising because CD Extremadura were founded in 2022 as a replacement for the defunct UD Extremadura.

Extremadura vs Sevilla Match Prediction 04 December 2025

Sevilla will be desperate to make up for their heartbreaking loss to Real Betis, and given Extremadura's defensive woes, we predict Alexis Sanchez and teammates will turn it into a win over the low league team. Los Sevillanos did not impress in the Seville derby, losing to their bitter local rivals 2-0 at home. Unlike previous seasons, the away ratio of the Andalusians is similar to their home ratio. Brazilian defender Marcao withdrew from the local derby with an injury, but Kike Salas is certainly capable of filling the void. I expect a dominant performance by Seville and a confident win.

 Our initial prediction is W2 and over 2.5 goals at 2.05 odds from Bet365

 Our prediction is W2 and over 3.5 at 3.4 odds from the Betway

 Our final prediction will be correct score of 0:4 at 18.5 odds from 1xbet