Chile vs Uruguay Prediction: The hosts to continue their poor form

Chile vs Uruguay: Prediction and odds on the Match on 10 September 2025

Chile and Uruguay will lock horns in the early hours of Tuesday, 10 September 2025, at the Estadio Nacional Julio Martínez Pradanos. The hosts have failed to score in each of their last five games. Can they return to their scoring form? Below, you will find the team news, possible starting lineup, head-to-head statistics, interesting facts, betting tips, and odds.

Chile: form and statistics

Chile suffered a 3-0 loss to Brazil in their last game to continue their poor run. The Red One remains winless in their last five games, losing four and drawing one. Their old glory seems gone, but they have something to build on with the new set of young bloods in the squad. The poor form of the Chileans remains concerning despite the squad overhaul, having seen just two wins in their last 7 games. They have failed to score in each of their last five games, and they continue to suffer in front of goal. They sit bottom of the table with ten points in 17 games, scoring nine goals and conceding 27.

Chile: Team News and Injury Report

Chile are expected to be without Benjamin Kuscevic and Dario Osorio in this clash due to injuries. However, I expect the coach to continue with his 4-3-3 formation that will have Thomas Gillier in between the sticks.

🔖 Chile possible starting lineup (4-3-3)

Goalkeeper — Thomas Gillier

Defenders — Gabriel Suazo, Benjamín Kuscevic, Guillermo Maripán, Fabián Hormazábal

Midfielders — Felipe Loyola, Rodrigo Echeverría, Darío Osorio

Attackers — Alexander Aravena, Ben Brereton Díaz, Gonzalo Tapia

👤 Head coach: Nicolás Córdova

Uruguay: form and statistics

Uruguay have already booked their place in the 2026 FIFA World Cup. They secured a 3-0 win over Peru in their last game, with Rodrigo Aguirre opening the scoring in the 14th minute. Giorgian de Arrascaeta doubled the lead two minutes into the hour mark, and Federico Vinas made it 3-0 in the 80th minute. They are now unbeaten in six of their last eight games, but their away form has been concerning. They have remained without a win in their last six games on the road.

Uruguay: Team News and Injury Report

The Sky Blue is expected to have Ronald Araújo and Nahitan Nández back in the squad after their previous suspension. Darwin Núñez is expected to go back to the starting 11 after finishing her five-match suspension. However, Mathías Olivera is ruled out of this game due to accumulated yellow cards.

🔖 Uruguay possible starting lineup (4-3-3) 

Goalkeeper — Sergio Rochet

Defenders — Marcelo Saracchi, Santiago Bueno, José María Giménez, Guillermo Varela

Midfielders — Giorgian De Arrascaeta, Rodrigo Bentancur, Federico Valverde

Attackers — Maxi Araújo, Darwin Núñez, Facundo Pellistri

👤 Head coach: Marcelo Bielsa

Chile vs Uruguay: head-to-head statistics

Chile and Uruguay have met 15 times since 2007. Chile won four times, Uruguay won seven times, and four games ended in a draw. The last game between the two sides ended in a 3-1 win for Uruguay.

Chile vs Uruguay: Betting Tips & Odds

• Uruguay are unbeaten in their last five head-to-head games against Chile, with four wins. On the other hand, Chile have lost four and drawn one of their last five games in the qualifiers. A win or a draw for the visitors is 1.266 odds on 1xBet;
• Chile have not scored in their last five games in all competitions. A repeat of this outcome is available at 2.23 odds on 1xBet;
• Ten of the last 12 games of Uruguay have seen fewer than three goals. This option is available at 1.60 odds on 1xBet.

Chile vs Uruguay match prediction, 10 September 2025

Uruguay have already qualified for the 2026 FIFA, but I will still back them in this clash due to the poor form of the hosts. The hosts have not won any of their last five games and have even failed to find the back of the net. Although Uruguay might not have been superb on the road but playing against Chile should give them the motivation to continue with a win. 

Our match prediction: Both Teams to Score – NO for a coefficient of 1.634 in the 1xBet bookmaker.

Our betting tip on the match: A win for the visitors (Uruguay) at a coefficient of 1.95 in the Bet365 bookmaker.

Our final betting tip on the match: Under 2.5 goals for a coefficient of 1.60 in the Betway bookmaker.