Bayer Leverkusen vs Borussia Monchengladbach Prediction: Can Leverkusen deepen Gladbach woes?

Bayer Leverkusen vs Borussia Monchengladbach Prediction and Odds on 21 September 2025

At the BayArena, Leverkusen enter this fixture under pressure to assert dominance. Though their attack remains a threat, recent home performances have been mixed, with goals balanced by occasional defensive lapses. Against Gladbach, now under interim coach Eugen Polanski after a sacking, the visitors are severely depleted, and morale looks shaky. Monchengladbach's start to the campaign has been dire, with no goals and no wins, which shifts much of the favour toward Leverkusen. Leverkusen will aim to use their stronger squad depth and attacking creativity to punish Monchengladbach's vulnerabilities. This isn’t likely to be a high-scoring classic, but Leverkusen should have enough to break through if Gladbach can’t steady.

Bayer Leverkusen: Forms and Statistics

Leverkusen’s recent form is a mix of promise and concern: offensively sharp, often creating many chances and scoring well, but defensive lapses and occasional sluggish starts have left them vulnerable. At home, they average over 2 goals per game in recent fixtures, but concede roughly between 1 and 1.5, meaning matches have been less clean than ideal. 

Bayer Leverkusen - Lineups

🔖 Bayer Leverkusen Predicted Lineup (3-4-2-1)

Flekken; Quansah, Badé, Tapsoba; Vázquez, Tillman, García, Grimaldo; Tella, Ben Seghir; Schick

⛔️ Unavailable: Robert Andrich (suspended), Ezequiel Fernández (suspended), Martin Terrier (injury), Exequiel Palacios (injury), Nathan Tella (doubt)

👤 Head coach: Kasper Hjulmand

Borussia Monchengladbach: Forms and Statistics

Monchengladbach's away form this season looks fragile. Their lack of match sharpness in attack shows, they are creating shots, but finishing is poor. Defensively, they’ve been breached often, especially early on in games. Possession stats are decent in midfield, but depth is exposed with injuries, and morale is low after a poor run. They seem likely to defend deep, attempt counters, but may struggle to close spaces given Leverkusen’s width and midfield control.

Borussia Monchengladbach - Lineups

🔖 Borussia Monchengladbach Predicted Lineup (4-2-3-1)

Kauã; Collins, Koch, Theate, Brown; Larsson, Chaïbi; Doan, Uzun, Bahoya; Burkardt

⛔️ Unavailable: Tim Kleindienst (out), Niklas Swider (doubtful), Nathan N'Goumou (out), Wael Mohya (injury), Robin Hack (doubtful)

👤 Head coach: Eugen Polanski

Bayer Leverkusen vs Borussia Monchengladbach match prediction 21 September 2025

• In 7 of the last 8 games between Leverkusen and Monchengladbach, bet on over 2.5 goals has played. The bet is offered on the Betway bookmaker website for odds of 1.49 odds;
• In 5 of the last 7 games between Leverkusen and Monchengladbach, bet on BTTS has played. The bet is offered on the Betway bookmaker website for odds of 1.58 odds;

Bayer Leverkusen vs Borussia Monchengladbach match prediction 21 September 2025

Leverkusen have consistently beaten Mönchengladbach in recent seasons. The H2H statistics of the last 11 Bundesliga games show that Leverkusen have yet to lose against them. When these teams meet at the BayArena, Leverkusen often dominate possession and create more chances, though Mönchengladbach have occasionally held firm, especially early in games. 

Leverkusen’s recent home form has had struggles, as evidenced by the team losing and winning games. The team also has a tendency to concede at least once, even when scoring. Mönchengladbach, away, have created chances but lack finishing sharpness.

We anticipate that Leverkusen will win after 90 minutes with a scoreline of 3-0 or 2-0.

Below are our predictions

Our match prediction: is W1 to win for a coefficient of 1.61 in the Betway bookmaker.

Our betting tip on the match: is No BTTS for a coefficient of 2.40 in the Bet365 bookmaker.

Lastly: is under 3.5 goals for a coefficient of 1.70 in the 1XBet bookmaker.