Borussia Dortmund vs RB Leipzig Prediction: Dortmund will aim to edge Leipzig in a game of high importance

Borussia Dortmund vs RB Leipzig: Prediction for the Match on October 04, 2025

Dortmund come into this match in excellent form as they are unbeaten across this season in the Bundesliga. With several wins at Signal Iduna Park and relying on a strong attacking core that includes Serhou Guirassy and Karim Adeyemi, Dortmund has a strong offensive unit. However, they are missing a few key players through injury, which could test their depth. 

For Leipzig, they have bounced back impressively since an early-season setback, showing resilience and defensive improvement away from home. Yet they too have injury concerns, especially in defence and midfield, that may hamper their balance. This promises to be a fast-paced, open match where transitions, set-pieces, and who handles pressure could decide the outcome.

Borussia Dortmund: Forms and Statistics

Dortmund are showing strong home form with consistent wins, relatively solid defensive displays in home matches, and high attacking output. Dortmund has scored multiple goals frequently at Signal Iduna and tend to dominate possession there. Their unbeaten run at home gives them confidence. The main concern is coping without some injured players and maintaining concentration, particularly in defense.

Borussia Dortmund - Lineups

🔖 Borussia Dortmund Predicted Lineup (3-4-2-1)

Kobel; Anton, Schlotterbeck, Bensebaini; Ryerson, Sabitzer, Nmecha, Svensson; Adeyemi, Beier; Guirassy

⛔️ Unavailable: Emre Can (out), Julien Duranville (out), Niklas Süle (out), Fábio Silva (doubtful), Aaron Anselmino (doubtful)

👤 Head coach: Niko Kovač

RB Leipzig: Forms and Statistics

Leipzig have alternated between impressive attacking displays and frustrating goal droughts in away games. Their offensive potential is high, with players regularly creating chances, but defensive lapses and failure to score early cost them. Their away record vs Mainz has been mixed, and they’ll likely need to control possession and avoid being stretched in transitions

Leipzig - Lineups

🔖 Leipzig Predicted Lineup (4-2-3-1)

Gulácsi; Raum; Baku, Orbán, Lukeba; Schlager, Seiwald; Bakayoko, Nusa, Baumgartner; Rômulo

⛔️ Unavailable: Henrichs, Banzuzi, Haidara

👤 Head Coach: O. Werner

Borussia Dortmund vs RB Leipzig match prediction 04 October 2025

• In 8 of the last 10 games between Borussia Dortmund and RB Leipzig, bet on over 2.5 goals has played. The bet is offered on the Betway bookmaker website for odds of 1.34 odds;
• In 5 of the last 6 games between Borussia Dortmund and RB Leipzig, bet on over 4.5 cards has played. The bet is offered on the Betway bookmaker website for odds of 1.46 odds;

Borussia Dortmund vs RB Leipzig match prediction 04 October 2025

Dortmund are unbeaten so far this season, with several wins at home and clean sheets in most of their recent home league games. Leipzig has established good momentum since their rough start: multiple wins in a row, conceding very few, and improving defensively. Out of about 20 meetings, Dortmund have 9 wins, Leipzig 9, and 2 draws. At Dortmund, home advantage edges in favour of BVB, but recent matches have often been tight. Many of their recent fixtures have seen both teams score and produce high-scoring affairs.

This should be a tight, entertaining clash. Dortmund’s home strength and attacking depth make them slight favourites, but Leipzig have enough quality to make it close. Expect goals on both sides and a competitive match where momentum could swing late. After 90 minutes, a 2-1 or 3-1 win for Dortmund is expected. 

Below are our predictions

Our match prediction: is W1 to win for a coefficient of 1.72 in the Betway bookmaker.

Our betting tip on the match: is BTTS and over 2.5 goals for a coefficient of 1.62 in the Bet365 bookmaker.

Lastly: is over 9.5 corners for a coefficient of 1.83 in the 1XBet bookmaker.