Borussia Dortmund vs Wolfsburg Prediction: Dortmund may capitalize on the struggles of Wolfsburg

Borussia Dortmund vs Wolfsburg Prediction and Odds on 21 September 2025

Borussia Dortmund arrive at Signal Iduna Park with something to prove after letting leads slip in Europe, they will be focused on tightening up at the back and restoring confidence. Wolfsburg have made a decent start in the Bundesliga, picking up points and showing flashes, especially in attack. But their defensive weakness, inconsistencies, and away form remain an issue. 

With Dortmund expected to press high, exploit wings, and create space, this match may tilt heavily in favour of the home side.

Borussia Dortmund: Forms and Statistics

Dortmund are in strong shape at home and have scored multiple goals in most recent home league matches, often leading by halftime. Their attacking depth providing plenty of options, though the defence remains vulnerable especially with injured key defenders. They are confident at Signal Iduna, feeding off the crowd and pushing for dominance.

Borussia Dortmund - Lineups

🔖 Wolfsburg Predicted Lineup (3-4-3)

Kobel; Ryerson, Anton, Bensebaini; Couto, Sabitzer, Bellingham, Svensson; Adeyemi, Guirassy, Beier

⛔️ Unavailable: Emre Can (injury), Nico Schlotterbeck (injury), Niklas Süle (injury), Fábio Silva (injury), Julien Duranville (injury), Aaron Anselmino (doubtful)

👤 Head coach: Niko Kovač

Wolfsburg: Forms and Statistics

The form of Wolfsburg away from home is patchy. While they have shown attacking capability, they have also failed to score in several away games and conceded too freely. Defensively, lapses at transition phases punish them as their offensive moments are promising but not yet consistent enough to challenge Dortmund regularly.

Wolfsburg - Lineups

🔖 Wolfsburg Predicted Lineup (4-2-3-1)

Grabara; Fischer, Jenz, Koulierakis, Mæhle; Arnold, Vinicius; Skov Olsen, Majer; Wimmer

Rønnow, Doekhi, Querfeld, Leite; Trimmel, Khedira, Haberer, Skov; Burke, Ansah

⛔️ Unavailable: Jesper Lindstrøm (doubtful), Denis Vavro (out), Rogério (out), Kevin Paredes (out)

👤 Head coach: Paul Simonis

Borussia Dortmund vs Wolfsburg match prediction 21 September 2025

• In 5 of the last 6 games between Borussia Dortmund and Wolfsburg, bet on under 4.5 cards has played. The bet is offered on the Betway bookmaker website for odds of 1.42 odds;
• In 4 of the last 5 games between Borussia Dortmund and Wolfsburg, bet on under 10.5 corners has played. The bet is offered on the Betway bookmaker website for odds of 1.59 odds;

Borussia Dortmund vs Wolfsburg match prediction 21 September 2025

Dortmund have been prolific lately as the team has 15 goals in their last five league matches. Wolfsburg have failed to score in four of their past six, and their away record has dropped. Historically, Dortmund dominate this game as evident in the fact that they have won the last five games with Wolfsburg. Games between these two sides tend to go over 2.5 goals, and both teams to score is often a live possibility.

Dortmund should win this one, based on home advantage, attacking momentum, and Wolfsburg’s defensive doubts. A scoreline of 3-1, 4-1 is possible. 

Below are our predictions

Our match prediction: is W1 to win for a coefficient of 1.63 in the Betway bookmaker.

Our betting tip on the match: is BTTS for a coefficient of 1.61 in the Bet365 bookmaker.

Lastly: is over 3 goals for a coefficient of 2.40 in the 1XBet bookmaker.