RB Leipzig vs Bayer Leverkusen Prediction: Will we see another goal-fest between these teams?

RB Leipzig vs Bayer Leverkusen: Prediction for the Match on December 20, 2025

The last big match of the German Bundesliga season in 2025 will pit two heavyweights against each other: RB Leipzig and Bayer Leverkusen. The teams were ready to challenge Bayern for the title, but that opportunity may have already passed. Now they are fighting for a place in the top four to secure a place in next year's Champions League. Bayer has four players called up to the African national teams for the Africa Cup of Nations. Leipzig has only two, but they, too, are struggling with a series of injuries. That makes things difficult for both sides, especially in a direct battle for those crucial Champions League spots. A win here is crucial, but squad issues can shut down a game and affect the spectacle.

RB Leipzig: Form and Statistics

Ole Werner and his team have a lot to think about. There have been rumours in Germany recently that RB Leipzig could challenge Bayern for the title. Back then, the gap was surmountable. But they have won just two of their last five Bundesliga games (with two losses and one draw). Defeats to Hoffenheim and Union Berlin, as well as a draw with Borussia Mönchengladbach, are results that have killed any dreams of a title. They are currently nine points behind Bayern, so that is out of the question. The real alarm is whether they can stay in the top four, which is not guaranteed. With form like this, their rivals could replace them. Failure to beat Bayer Leverkusen in this round will only make matters worse. The manager is facing a squad problem. Benjamin Henrichs, Viggo Gebel, El Chadaille Bitshiabu, Assan Ouédraogo, and Antonio Nousa are all out of action, while Amadou Haidara and Yan Diomande have travelled to the AFCON.

RB Leipzig: Team News

🔖RB Leipzig predicted lineup (4-3-3): Peter Gulacsi (GK), Kosta Nedeljkovic, Willi Orban, Castello Lukeba, David Raum, Christoph Baumgartner, Nicolas Seiwald, Xaver Schlager, Andrija Maksimovic, Conrad Harder, Tidiam Gomis.

⛔️Out: Benjamin Henrichs, Viggo Gebel, El Chadaille Bitshiabu, Assan Ouédraogo, and Antonio Nousa (injured), Amadou Haidara and Yan Diomande (AFCON)

👤Head coach: Ole Werner

Bayer Leverkusen: Form and Statistics

Bayer's plight mirrors Leipzig's in some ways. It's hard to criticize them too much - they're in the Bundesliga's top 4, have reached the quarter-finals of the German Cup (beating Borussia Dortmund away), and are on the verge of securing a place in the Champions League play-offs. On paper, it sounds solid. However, if you dig deeper into each competition, only the Cup offers a real chance of winning a trophy. Their Champions League season has been a failure, and after 14 Bundesliga matches, they are already 12 points behind Bayern! This is not even close to what fans expected from Bayer at the start of the season. Of course, Kasper Hjulmand has stabilized the situation, but even under his leadership, problems on the pitch remain. There are also problems with the squad. The team's top scorer, Alejandro Grimaldo, is questionable due to injury. Jarell Quansah is also missing due to suspension, while Exequiel Palacios and Lucas Vázquez are still out of the squad. Also at AFCON are Edmond Tapsoba, Eliesse Ben Seghir, Ibrahim Maza, and Christian Kofane.

Bayer Leverkusen: Team News

🔖Bayer Leverkusen predicted lineup (4-4-2): Mark Flekken (GK), Jeanuel Belocian, Robert Andrich, Axel Tape-Kobrissa, Arthur, Aleix Garcia, Malik Tillman, Nathan Tella, Jonas Hofmann, Martin Terrier, Alejo Sarco.

⛔️Out: Alejandro Grimaldo, Jarell Quansah (suspension), Exequiel Palacios, and Lucas Vázquez (injured), Edmond Tapsoba, Eliesse Ben Seghir, Ibrahim Maza, and Christian Kofane (AFCON)

👤Head coach: Kasper Hjulmand

RB Leipzig vs Bayer Leverkusen: Head-to-Head Statistics

Since 2021, Leipzig and Leverkusen have played nine Bundesliga matches, and the balance is almost even: four wins for both teams and one draw. There is an average of over 3 goals scored per match, which suggests that the games open up quickly and offer many opportunities.

RB Leipzig vs Bayer Leverkusen: Betting Tips & Odds

• In their last four matches over 3.5 goals were scored. You can bet on over 3.5 goals for odds of 2.45 at BC.Game;
• In their last four matches both teams scored and over 3.5 goals were scored. You can bet on BTTS and over 3.5 goals for odds of 2.7 at 1xbet;
• RB Leipzig won in theil last five matches at home in all competitions. You can bet on RB Leipzig to win for odds of 2.3 at Betway.

RB Leipzig vs Bayer Leverkusen Match Prediction 20 December 2025

The recent meetings between Leipzig and Bayer have been exciting and goal-filled. Five goals have been scored in three of the last four games over the past two seasons, four in the second. This fits perfectly with their attacking philosophy. Both teams are averaging more than two goals per game this season and conceding more than one. All signs point to a high-scoring game. The history of both teams' previous meetings and their form support the prediction of both teams being the top-scoring teams in the league.

Our match prediction: Over 3.5 goals for a coefficient of 2.45 in the BC.Game bookmaker.

Our betting tip on the match: BTTS and over 3.5 for a coefficient of 2.7 in the 1xbet bookmaker.

Our final betting tip on the match: Correct score 2:2, for a coefficient of 11.9 in the Betway bookmaker.