Inter vs Sassuolo Prediction: Expecting Manmy Goals

Inter vs Sassuolo: Prediction for the Match on September 21, 2025

The match between Inter Milan and Sassuolo will conclude the Sunday program of the fourth round of the Italian Serie A championship. Will Inter confidently maintain their status as favorites, or will Sassuolo surprise everyone? Read our free preview for this game to find out. Let's take a look at the statistical trends, odds, and betting lines, and choose a few betting options.

Inter: form and statistics

Inter played their last game last Wednesday, starting in the Champions League against Ajax on the road. They achieved a comfortable victory of 2-0, with Markus Thuram scoring a goal in each half. This was a partial recovery for Inter after their disappointing start to the season, as they had only three points in their first three games. In the opening game, they beat Torino 5-0, but then lost 1-2 to Udinese and 3-4 to Juventus.

Sassuolo: form and statistics

Neroverdi won Serie B last season by a clear margin. Fabio Grosso's team also plays in the top division. Sassuolo began the championship with a disappointing loss to Napoli (0-2), but then they only lost to Cremonese (2-3) at the end, and they won their first victory of the season in the previous round - the black and greens defeated Lazio (1-0). Aliu Fader scored the only goal in the 70th minute.

Inter vs Sassuolo: head to head statistics

Sassuolo and Inter played 24 games against each other. They both have 11 victories each and two draws. In the past ten head-to-head meetings, Inter won six times, Sassuolo won three times, and there was one draw.

Inter vs Sassuolo: Betting Tips & Odds

• In seven of the twelve previous Inter games, the total score was higher. The betting option is TO (2.5) with odds of 1.57.
• In six of the last seven games, Inter scored at least twice. The betting option IT1O (1.5) has odds of 1.38.
• In eight out of ten previous encounters, Sassuolo did not score or concede goals. The option "BTTS- No" has odds of 1.77.

Inter vs Sassuolo: Bookmakers' odds for the match

In the past 3 out of 5 matches, Inter have not missed. The ITM2 (0.5) rate with a coefficient of 1.88 is offered by the bookmaker 1xbet. Inter are the clear favorites for the upcoming match, with the odds on their victory offered by 1xbet at 1.30. On the other hand, the odds for Sassuolo are 11.00, and the draw is estimated at 5.60. 

Inter vs Sassuolo Match Prediction 21 September 2025

Sassuolo has traditionally been an uncomfortable opponent for Inter, so we will not be betting on the outcome in this case. Instead, let's look at the goals. These matches often result in a high number of goals. In fact, in 8 out of the 11 previous head-to-head meetings between the two teams, at least 3 goals were scored, and Sassuole scored against Inter in 9 out of the last 11 games.

Our main prediction: TO (2.75) for a coefficient of 1.75 in the betway bookmaker.

Our betting tip on the match: IT2O (0.5) for a coefficient 1.80 in the 1xbet bookmaker.

Our final betting tip on the match: Correct Score 3:1 for a coefficient 11.00 in the bet365 bookmaker.