Lazio vs Roma Prediction: Will the Teams Share Points?

Lazio vs Roma: Prediction for the Match on September 21, 2025

The central match of the fourth round of the Italian Championship will be the Rome Derby - Lazio vs Roma. Who will come out on top in this clash of fierce opponents? We offer you a free prediction. Let's take a look at the form of the teams, odds and betting lines, statistical trends and choose several options at once.

Lazio: form and statistics

Before the start of the season, Maurizio Sarri returned to the helm of Biancocelesti, but so far, the coaching change has not paid off. The Roman side has only managed to score three points so far. First, they lost to Como away (0-2), then beat Verona at home (4-0), and then failed to defeat Sassuolo unexpectedly (0-1). Also, this season, Lazio is not competing in European competitions, so they can fully focus on the domestic league. With this in mind, there is little doubt that Lazio will recover their lost ground during the season.

Roma: form and statistics

Gialorossi has started this season with a new head coach, Gian Piero Gasperini, and so far, they are doing well, unlike Lazio. In the opening two rounds, Roma scored two victories with a score of 1:0 - at home over Bologna and away over Pisa. However, the third round slightly spoiled the picture - Roma lost 0:1 to Torino on their own field. Next week, Roma will start in European competitions, where they will play against Nice in the first round of the Europa League.

Lazio vs Roma: head to head statistics

Roma has played 185 matches in total, with 69 wins and 51 losses, as well as 65 draws. In the last ten meetings between the two teams, Roma and Lazio each have four wins and two draws. The bookmaker's prediction for the next game is (2.5), with a coefficient of 1.70.

Lazio vs Roma: Betting Tips & Odds

• In seven of the previous ten games, Roma have not conceded a goal. The ITU (0.5) bet has a coefficient of 2.85.
• Eight of the last eleven matches have ended in a win for Roma, with a W2 bet having a coefficient of 2.65.
• In 8 of the last 9 meetings between Lazio and Roma, there has been no goal exchange. The odds are "no goal" with a coefficient of 1.88.

Lazio vs Roma: Bookmakers' odds for the match

Roma is the small favorite for the upcoming game, with the odds of their victory offered by the Fonbet bookmaker at 2.65. Betting on Lazio is available at 2.85, while the odds for a draw are 3.20. The game is expected to be low-scoring, with a total goals market (TU) of 2.5 accepted at a coefficient of 1.68 and a bet on both teams scoring at least one goal (TO) set at 2.20. Betting "both teams will score" is estimated at 1.92, while betting "neither team will score" goes for 1.88.

Lazio vs Roma Match Prediction 21 September 2025

At the beginning of the season, Roma appears to be a more balanced team compared to Lazio, but Biancocelesti has a deficit in points when considering goal expectation statistics. Therefore, a draw seems like the most likely outcome for this game, and we also expect a low number of goals. Like in the previous seven Roman derbies, we believe this one will be low-scoring.

Our main prediction: Total Under 2.5 for a coefficient of 2.30 in the betway bookmaker.

Our betting tip on the match: Draw for a coefficient 3.22 in the 1xbet bookmaker.

Our final betting tip on the match: Correct Score 1:1 for a coefficient 6.00 in the bet365 bookmaker.