Green Bay Packers vs Detroit Lions Prediction: Lions confident of repeating history

Green Bay Packers vs Detroit Lions Prediction and Odds on the Match on September 07, 2025

In the opening round of the National Football League 2025, Green Bay Packers will play Detroit Lions at Lambeau Field in the National Football Conference. The two teams made the post season last year but could not get past the early stage. How will this opener end? I will look into the match previews from betting perspectives and justify the options that have been chosen. 

Green Bay Packers: Form and Statistics

The Green Bay Packers did not have an easy 2024 season and needed to give their all to make the National Football Conference the Wild Card as they finished third. However, the previous year showed an improvement to the team we saw in 2023 with a 9-8 record, this time finishing 11-6 during the regular-season. However, their postseason performance was cut short as they could not get past Philadelphia Eagles in the ⅛ finals.  

During the preseason, the Green Bay Packers struggled against the New York Jets, scoring just ten points and ended up losing by 20 points. However, we saw an improved side that still needed a better offensive touch against the Indianapolis Colts and Seattle Seahawks having picked a 19-23, and 20-7 wins respectively. 

Green Bay Packers Team News

The Packers have a number of questionable starters for this game. Nate Hobbs, Jayden Reed, Dontayvion Wicks, Savion Williams, Zayne Anderson, Barryn Sorrell and Micah Parsons might not make the team for this opening game. Meanwhile, Jordan Love with a left thumb injury and Elgton Jenkins with hip issues are expected to start this game having trained with the team during the week despite not receiving a pass. 

Detroit Lions: Form and Statistics

The Detroit Lions were one of the few standouts in the National Football League last season and will hope they could get their way this year. In the regular season, this team finished with a 15-2 record where they lost to the Tampa Bay Buccaneers and Buffalo Bills and then remained a strong contender for the NFL title in the postseason. However, they were shocked by the Washington Commanders in divisional playoffs with their downfall coming in the second and fourth quarters in a game that ended 31-45. 

In the Hall of Fame this year, the Detroit Lions opened their preseason with a disappointing 34-7 defeat and then went to defeat the Falcons 10-7. Yet, they could not prove themselves in the last two games, losing to the Miami Dolphins before only scoring seven points against the Houston Texans. 

Detroit Lions Team News

The Detroit Lions have three players ruled out of this Sunday’s fixture. Trevor Nowaske who is dealing with elbow problems, Jamarco Jones whose ankle broke and Sione Vaki with a hamstring will not make the squad. However, Isaac TeSlaa and Kayode Awosika are names expected to make the team list despite not receiving a status prior to this writing after making full training participation. 

Green Bay Packers vs Detroit Lions Betting Tips & Odds

• The Green Bay Packers have not had the best of their games against the Detroit Lions in recent times with just one win in their last seven meetings. Yet, the home team has had a brilliant preseason and are favourites here. The moneyline for the hosts is set at 1.74 on Betway.
• The Detroit Lions might not be the favourites in this game but they could repeat history with four wins in the last five games of this fixture. Also, the Detroit Lions have won each of their last eight road games minus preseason and have their moneyline set at 2.10 on Bet365.
• The total for the past games of this fixture has always been over 40 and this game does not look like it will be different. Over 40.5 total points has a 1.34 odds on 1Xbet.

Green Bay Packers vs Detroit Lions Match Prediction 07 September 2025

It is surprising the Green Bay Packers come into this fixture as favourites despite the Detroit Lions having won most of their recent meetings. However, from their preseason performances, the Detroit Lions looked very shaky and in the first game of the season on the road, it will be tough to pick them. You can make a case here given openers can go either way especially with the Green Bay Packers having to give so much offensively after struggling in their preseason games. Yet, I believe we will see a different approach from both teams and the total should go over. 

Our match prediction is a moneyline win for the Green Bay Packers with odds at 1.76 on 1Xbet bookmaker. 

Our betting tip is a win for the Green Bay Packers in the third quarter with odds at 1.74 on Bet365 bookmaker. 

Our final match prediction is over 44.5 total points with odds at 1.62 on Betway bookmaker.