Los Angeles Rams vs Houston Texans Prediction: Tough opener for two incredible sides

Los Angeles Rams vs Houston Texans Prediction and Odds on the Match on September 07, 2025

The National Football League is back and in one of round one fixtures, the Houston Texans will travel to play Los Angeles Rams at SoFi Stadium. This will be an interconference clash with the two teams hoping for a better season after making the playoffs last year. How will this game unfold? I will look into the match previews from betting perspectives and justify the options that have been chosen. 

Los Angeles Rams: Form and Statistics

The Los Angeles Rams had a brilliant regular season the previous year and they will hope they can start this season on the right track. In 17 games, the Los Angeles Rams finished with a 10-7 record despite starting their season with four losses in their first five openers and then finished top of the NFC West standings. In their victories, this team defeated the San Francisco 49ers (2), Las Vegas Raiders, Minnesota Vikings, Seattle Seahawks, New England Patriots, New Orleans Saints, Buffalo Bills, New York Jets Jets, and Arizona Cardinals. However, they could not get past the second round of the playoffs against the Philadelphia Eagles who went on to win the league despite a 27-9 win over the Vikings in their opener. 

However, their preseason run saw them secure consecutive wins over Dallas Cowboys and Los Angeles Chargers before losing the last one by two points to Cleveland Browns. 

Los Angeles Rams Team News

Quarterback Matthew Stafford had a sore back which kept him out of the preseason games but the Super Bowl winner is cleared to start his 17th season in the NFL and fifth with the Rams. The pro will be a player to watch after an incredible performance last season that saw him throw for 3,762 yards and 20 touchdowns against eight touchdowns. He helped the Rams win the National Football Conference while pulling off 533 yards and four scores in the playoffs. 

Regarding injuries, Alaric Jackson is not expected to feature in this opening game with the left tackle facing a recurrence of blood clots which has kept him out of training camp and much of the preseason. 

Houston Texans: Form and Statistics

The Houston Texans just like the Los Angeles Rams also finished with a 10-7 record last season and ended the season topping the American Football Conference standing. The Houston Texans did have a solid start that saw them lose just one of the first six games of the season and then went 5-6 in their last eleven games of the season. In their wins, the Houston Texans defeated Indianapolis Colts twice, Chicago Bears, Jacksonville Jaguars twice, Buffalo Bills, New England Patriots, Dallas Cowboys, Miami Dolphins, and Tennessee Titans. Despite having a win in their first playoff against the Los Angeles Chargers their 23014 defeat in the postseason quarterfinals to Kansas City Chiefs ended their hope. 

In preseason ahead of this game, the Houston Texans secured two wins despite opening it with a 20-10 defeat to the Minnesota Vikings. 

Houston Texans Team News

Nick Chubb is the big name in this Texans squad and is expected to lead his side in attack with Joe Mixon expected to miss the first month of the season due to a foot injury.

Gardner-Johnson did well to recover from a knee injury he picked up early August and will be part of the squad in this opener. Moreso, there is good news regarding Cam Robinson who is confirmed fully fit despite a brief illness that kept him out of training last week. However, Christian Kirk and Braxton Berrios are the names on the injury list with both players dealing with hamstring. 

Los Angeles Rams vs Houston Texans Betting Tips & Odds

• The Houston Texans won the last two meetings of this fixture. Meanwhile, the bookies are tagging them as underdogs in this road fixture. Yet, their performances last season show they can pull off surprising upset. Bet365 set the moneyline for the visitors at 2.45.
• Each of the last five meetings between Los Angeles Rams and Houston Texans have ended with at least 30 points. The total is set at over in this game with 39.5 points available on 1Xbet at 1.50 odds.
• The Houston Texans have scored at least 17 points in four of the last five games of this fixture. Over 17.5 points for this game is available on 1Xbet with odds at 1.61.
• The Los Angeles Rams have had the upper hand in the history of this fixture. Having struggled in the last meetings, I believe opening the season with this kind of fixture is a good one as they will be full of energy and confidence. A win for the Los Angeles Rams as home favourites is available with odds at 1.60 on Betway.

Los Angeles Rams vs Houston Texans Match Prediction 07 September 2025

The Houston Texans have proven stubborn in this fixture especially considering how they defeated the Rams in their preseason meeting in 2024. However, I am confident the Los Angeles Rams will get the job done in this opener as they come in as favourites while also playing at home. Meanwhile the Los Angeles Rams have some injuries to deal with, Texans might look to take advantage here as we should expect a high point. 

Our match prediction is a moneyline win for the Los Angeles Rams with odds at 1.60 on Betway bookmaker.

Our betting tip is over 43.5 points with odds at 1.90 on Bet365 bookmaker. 

Our final match prediction is Houston Texans over 17.5 points with odds at 1.61 on 1Xbet bookmaker.