Tampa Bay Buccaneers vs San Francisco 49ers Prediction: Can Eddy Piñeiro score over 6.5 kicking points?

Tampa Bay Buccaneers vs San Francisco 49ers: Prediction for the match on October 12, 2025

The Buccaneers are 4-1, but they have only won by three points or less in all four of their games. They won their last home game as favorites, 29-27, against the Jets, but they didn't cover the -6.5 spread. In their only loss, a 26-21 loss to Jacksonville, San Francisco also kept things close. This game is likely to be close, and it wouldn't be surprising if the winner only wins by three points or less. Both teams should score a few times, but San Francisco's second field goal will probably be the most important one. Here at Telecomasia, we will preview this game and offer the best betting opportunities.

Buccaneers: Form and Statistics

The Buccaneers have had a lot of injuries, but they were still able to beat the Seahawks on the road last week. They didn't have their starting running back, Bucky Irving, or their wide receiver, Mike Evans. The Eagles, who won the Super Bowl, were the only team to beat Tampa Bay. The 49ers, on the other hand, have won four games, but each one was by five points or fewer, which shows that they aren't playing at their best. This season, Rachaad White has run for 149 yards and scored three touchdowns. He gets 29.8 yards per game on average. Emeka Egbuka has 445 receiving yards and five touchdowns, which puts him fourth in the NFL. He runs for 89 yards every game.

Buccaneers: Team News

Tykee Smith has 39 tackles, two tackles for loss (TFL), and one sack this season on defense. Lavonte David has made 34 tackles, four tackles for loss, 1.5 sacks, and one interception. SirVocea Dennis has made 33 tackles and four TFLs. Zyon McCollum has made 31 tackles and one TFL. Baker Mayfield is fourth in the NFL this season with 1,283 passing yards. He has also thrown 10 touchdowns, which is third in the league, and only one interception. He completes 65.1% of his passes and throws for an average of 256.6 yards per game and 7.5 yards per attempt.

San Francisco 49ers: Form and Statistics

The San Francisco 49ers have a big game against the Buccaneers coming up, but their starting quarterback, Brock Purdy, will miss it again. Even though he hurt his knee, backup quarterback Mac Jones is expected to play. The Buccaneers have already won some close games this season, so they might have an edge over the 49ers, who are not at full strength this week. This season, Christian McCaffrey has run for an average of 56.4 yards per game, for a total of 282 yards. But he hasn't scored a rushing touchdown yet. McCaffrey has also caught 39 passes for 387 yards, which is the most for the 49ers and the sixth most in the NFL. He has three touchdown catches and averages 77.4 yards per game. Adrian Martinez, who is San Francisco's third-string quarterback and was not drafted, has never thrown a pass in the regular season. Coach Kyle Shanahan will hope that Jones can play as well as he did in last week's 26-23 overtime win over the Rams, when Purdy was out.

San Francisco 49ers: Team News

Jones has thrown for 905 yards, six touchdowns, and one interception. He throws 66.7% of his passes and gains an average of 301.7 yards per game. Jake Tonges has caught 19 passes for 166 yards and three touchdowns. Brock Purdy has thrown for 586 yards, scored four touchdowns, and thrown four picks. He throws for an average of 293 yards per game and completes 65.8% of his passes. Fred Warner is the 49ers' best tackler with 50 tackles and two tackles for loss (TFL). He is fourth in the NFL.

Tampa Bay Buccaneers vs San Francisco 49ers Betting Tips & Odds

• In their last five matchups, San Francisco has won four times against Tampa Bay. Tampa Bay has been outscored by 40 points in those games.
• This season, Tampa Bay has won three of five games against the spread. However, they haven't covered when favored by 3.5 points or more, with an 0-1 record in such situations.
• Tampa Bay has gone over the set point total in 60% of their games this year, hitting the over three times in five games. The Buccaneers have also won both games where they were moneyline favorites, with a 64.9% chance of winning in this matchup.
• San Francisco has covered the spread three times in five games with a set total. As underdogs by 3.5 points or more, the 49ers covered the spread in their only such game this season.
• They've hit the over in three games this year and won their only game as underdogs. The implied probability of a San Francisco win is 39.4%.
• In five games, Dee Winters has made 36 tackles and three TFL. In five games, Marques Sigle has made 39 tackles. Bryce Huff has the most sacks for the 49ers, with three. He also has four TFL and 13 tackles.
• Bucky Irving has two touchdowns, 237 rushing yards, and 193 receiving yards. He runs for an average of 59.3 yards per game. White has caught 12 passes for 64 yards, but he hasn't scored a touchdown yet.

Tampa Bay Buccaneers vs San Francisco 49ers Match Prediction 12th October 2025

In Week 6, the San Francisco 49ers will play the Tampa Bay Buccaneers. The 49ers got good news about Brock Purdy's injury on Thursday, but the betting odds didn't change. There are no more unbeaten teams in the NFL since the Bills and Eagles lost last week. The 49ers will visit the Buccaneers on Sunday, and both teams are currently 4-1, making them two of the best.

Our match prediction is +3.0 Handicap San Francisco 49ers with odds at 2.00 on the 1Xbet bookmaker.

Our betting tip is Over 47.0 Total with odds at 1.90 on the Bet365 bookmaker.

Our final match prediction is the Tampa Bay Buccaneers to win with odds at 1.60 on the Betway bookmaker.